Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Patients with Cystic Fibrosis and One or Two F508del Alleles.

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Title: Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Patients with Cystic Fibrosis and One or Two F508del Alleles.
Authors: Graeber SY; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, and Cystic Fibrosis Center, and.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Lung Research (DZL), associated partner site, Berlin, Germany., Renz DM; Department for Radiology., Stahl M; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, and Cystic Fibrosis Center, and.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Lung Research (DZL), associated partner site, Berlin, Germany., Pallenberg ST; Department for Pediatric Pneumology, Allergology, and Neonatology.; German Center for Lung Research, Biomedical Research in Endstage and Obstructive Lung Disease (BREATH)., Sommerburg O; Division of Pediatric Pulmonology and Allergy and Cystic Fibrosis Center, Department of Pediatrics.; Department of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), and., Naehrlich L; Department of Pediatrics, Justus-Liebig-University Giessen, Giessen, Germany; and.; Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Giessen, Germany., Berges J; Division of Pediatric Pulmonology and Allergy and Cystic Fibrosis Center, Department of Pediatrics.; Department of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), and., Dohna M; Department for Radiology., Ringshausen FC; German Center for Lung Research, Biomedical Research in Endstage and Obstructive Lung Disease (BREATH).; Department for Pneumology, and., Doellinger F; Department of Radiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Vitzthum C; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, and Cystic Fibrosis Center, and.; German Center for Lung Research (DZL), associated partner site, Berlin, Germany., Röhmel J; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, and Cystic Fibrosis Center, and.; German Center for Lung Research (DZL), associated partner site, Berlin, Germany., Allomba C; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, and Cystic Fibrosis Center, and.; German Center for Lung Research (DZL), associated partner site, Berlin, Germany., Hämmerling S; Division of Pediatric Pulmonology and Allergy and Cystic Fibrosis Center, Department of Pediatrics., Barth S; Department of Pediatrics, Justus-Liebig-University Giessen, Giessen, Germany; and.; Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Giessen, Germany., Rückes-Nilges C; Department of Pediatrics, Justus-Liebig-University Giessen, Giessen, Germany; and.; Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Giessen, Germany., Wielpütz MO; Department of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), and.; Department of Diagnostic and Interventional Radiology, University of Heidelberg, Heidelberg, Germany., Hansen G; Department for Pediatric Pneumology, Allergology, and Neonatology.; German Center for Lung Research, Biomedical Research in Endstage and Obstructive Lung Disease (BREATH).; Cluster of Excellence RESIST (EXC 2155), German Research Foundation (DFG), Hannover Medical School, Hannover, Germany., Vogel-Claussen J; Department for Radiology.; Department for Pediatric Pneumology, Allergology, and Neonatology., Tümmler B; Department for Pediatric Pneumology, Allergology, and Neonatology.; German Center for Lung Research, Biomedical Research in Endstage and Obstructive Lung Disease (BREATH)., Mall MA; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, and Cystic Fibrosis Center, and.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Lung Research (DZL), associated partner site, Berlin, Germany., Dittrich AM; Department for Pediatric Pneumology, Allergology, and Neonatology.; German Center for Lung Research, Biomedical Research in Endstage and Obstructive Lung Disease (BREATH).
Source: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2022 Aug 01; Vol. 206 (3), pp. 311-320.
Publication Type: Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1535-4970
DOI:10.1164/rccm.202201-0219OC