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Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.

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Title: Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
Authors: Xia Y; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Prokop S; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Department of Pathology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Bell BM; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Gorion KM; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Croft CL; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Nasif L; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Xu G; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Riffe CJ; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Manaois AN; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Strang KH; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Quintin SS; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Paterno G; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Tansey MG; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Borchelt DR; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Golde TE; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA., Giasson BI; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. bgiasson@ufl.edu.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. bgiasson@ufl.edu.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. bgiasson@ufl.edu.
Source: Communications biology [Commun Biol] 2022 May 12; Vol. 5 (1), pp. 446. Date of Electronic Publication: 2022 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
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  Data: Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
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  Data: <searchLink fieldCode="AU" term="%22Xia+Y%22">Xia Y</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Prokop+S%22">Prokop S</searchLink>; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Department of Pathology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Bell+BM%22">Bell BM</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Gorion+KM%22">Gorion KM</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Croft+CL%22">Croft CL</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Nasif+L%22">Nasif L</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Xu+G%22">Xu G</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Riffe+CJ%22">Riffe CJ</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Manaois+AN%22">Manaois AN</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Strang+KH%22">Strang KH</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Quintin+SS%22">Quintin SS</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Paterno+G%22">Paterno G</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Tansey+MG%22">Tansey MG</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Borchelt+DR%22">Borchelt DR</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Golde+TE%22">Golde TE</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Giasson+BI%22">Giasson BI</searchLink>; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. bgiasson@ufl.edu.; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. bgiasson@ufl.edu.; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. bgiasson@ufl.edu.
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