View in EDS

A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells.

Saved in:
Bibliographic Details
Title: A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells.
Authors: Garreta E; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Prado P; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Stanifer ML; Department of Infectious Diseases, Molecular Virology, Heidelberg University Hospital, Heidelberg, Germany; Research Group 'Cellular Polarity and Viral Infection,' German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL, USA., Monteil V; Karolinska Institute and Karolinska University Hospital, Unit of Clinical Microbiology, 17182 Stockholm, Sweden., Marco A; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Ullate-Agote A; Área de Hemato-Oncología, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Universidad de Navarra, 31008 Pamplona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain; Departamento de Hematología, Clínica Universidad de Navarra, Universidad de Navarra, 31008 Pamplona, Spain., Moya-Rull D; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Vilas-Zornoza A; Área de Hemato-Oncología, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Universidad de Navarra, 31008 Pamplona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain; Departamento de Hematología, Clínica Universidad de Navarra, Universidad de Navarra, 31008 Pamplona, Spain., Tarantino C; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Romero JP; Área de Hemato-Oncología, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Universidad de Navarra, 31008 Pamplona, Spain., Jonsson G; IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria., Oria R; Center for Bioengineering and Tissue Regeneration, UCSF, San Francisco, CA, USA., Leopoldi A; IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria., Hagelkruys A; IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria., Gallo M; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., González F; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Domingo-Pedrol P; Internal Medicine Department, Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Spain., Gavaldà A; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona and CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain., Del Pozo CH; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Hasan Ali O; Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada; Department of Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Institute of Immunobiology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland., Ventura-Aguiar P; Nephrology and Kidney Transplant Department, Hospital Clínic Barcelona, Barcelona, Spain; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació Clínic per a la Recerca Biomèdica (FCRB), Barcelona, Spain., Campistol JM; Nephrology and Kidney Transplant Department, Hospital Clínic Barcelona, Barcelona, Spain; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació Clínic per a la Recerca Biomèdica (FCRB), Barcelona, Spain., Prosper F; Área de Hemato-Oncología, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Universidad de Navarra, 31008 Pamplona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain; Departamento de Hematología, Clínica Universidad de Navarra, Universidad de Navarra, 31008 Pamplona, Spain., Mirazimi A; Karolinska Institute and Karolinska University Hospital, Unit of Clinical Microbiology, 17182 Stockholm, Sweden; National Veterinary Institute, Uppsala, Sweden. Electronic address: ali.mirazimi@ki.se., Boulant S; Research Group 'Cellular Polarity and Viral Infection,' German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL, USA; Department of Infectious Diseases, Virology, Heidelberg University Hospital, Heidelberg, Germany. Electronic address: s.boulant@ufl.edu., Penninger JM; IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria; Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada. Electronic address: josef.penninger@ubc.ca., Montserrat N; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain; Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, Madrid, Spain. Electronic address: nmontserrat@ibecbarcelona.eu.
Source: Cell metabolism [Cell Metab] 2022 Jun 07; Vol. 34 (6), pp. 857-873.e9. Date of Electronic Publication: 2022 May 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 35561674
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Garreta+E%22">Garreta E</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Prado+P%22">Prado P</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Stanifer+ML%22">Stanifer ML</searchLink>; Department of Infectious Diseases, Molecular Virology, Heidelberg University Hospital, Heidelberg, Germany; Research Group 'Cellular Polarity and Viral Infection,' German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Monteil+V%22">Monteil V</searchLink>; Karolinska Institute and Karolinska University Hospital, Unit of Clinical Microbiology, 17182 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Marco+A%22">Marco A</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ullate-Agote+A%22">Ullate-Agote A</searchLink>; Área de Hemato-Oncología, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Universidad de Navarra, 31008 Pamplona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain; Departamento de Hematología, Clínica Universidad de Navarra, Universidad de Navarra, 31008 Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Moya-Rull+D%22">Moya-Rull D</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Vilas-Zornoza+A%22">Vilas-Zornoza A</searchLink>; Área de Hemato-Oncología, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Universidad de Navarra, 31008 Pamplona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain; Departamento de Hematología, Clínica Universidad de Navarra, Universidad de Navarra, 31008 Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Tarantino+C%22">Tarantino C</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Romero+JP%22">Romero JP</searchLink>; Área de Hemato-Oncología, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Universidad de Navarra, 31008 Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Jonsson+G%22">Jonsson G</searchLink>; IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Oria+R%22">Oria R</searchLink>; Center for Bioengineering and Tissue Regeneration, UCSF, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Leopoldi+A%22">Leopoldi A</searchLink>; IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hagelkruys+A%22">Hagelkruys A</searchLink>; IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Gallo+M%22">Gallo M</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22González+F%22">González F</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Domingo-Pedrol+P%22">Domingo-Pedrol P</searchLink>; Internal Medicine Department, Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gavaldà+A%22">Gavaldà A</searchLink>; Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona and CIBER Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Del+Pozo+CH%22">Del Pozo CH</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Hasan+Ali+O%22">Hasan Ali O</searchLink>; Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada; Department of Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Institute of Immunobiology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ventura-Aguiar+P%22">Ventura-Aguiar P</searchLink>; Nephrology and Kidney Transplant Department, Hospital Clínic Barcelona, Barcelona, Spain; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació Clínic per a la Recerca Biomèdica (FCRB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Campistol+JM%22">Campistol JM</searchLink>; Nephrology and Kidney Transplant Department, Hospital Clínic Barcelona, Barcelona, Spain; Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació Clínic per a la Recerca Biomèdica (FCRB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Prosper+F%22">Prosper F</searchLink>; Área de Hemato-Oncología, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Universidad de Navarra, 31008 Pamplona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain; Departamento de Hematología, Clínica Universidad de Navarra, Universidad de Navarra, 31008 Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Mirazimi+A%22">Mirazimi A</searchLink>; Karolinska Institute and Karolinska University Hospital, Unit of Clinical Microbiology, 17182 Stockholm, Sweden; National Veterinary Institute, Uppsala, Sweden. Electronic address: ali.mirazimi@ki.se.<br /><searchLink fieldCode="AU" term="%22Boulant+S%22">Boulant S</searchLink>; Research Group 'Cellular Polarity and Viral Infection,' German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL, USA; Department of Infectious Diseases, Virology, Heidelberg University Hospital, Heidelberg, Germany. Electronic address: s.boulant@ufl.edu.<br /><searchLink fieldCode="AU" term="%22Penninger+JM%22">Penninger JM</searchLink>; IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr-Gasse 3, 1030 Vienna, Austria; Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada. Electronic address: josef.penninger@ubc.ca.<br /><searchLink fieldCode="AU" term="%22Montserrat+N%22">Montserrat N</searchLink>; Pluripotency for Organ Regeneration, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain; Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, Madrid, Spain. Electronic address: nmontserrat@ibecbarcelona.eu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101233170%22">Cell metabolism</searchLink> [Cell Metab] 2022 Jun 07; Vol. 34 (6), pp. 857-873.e9. <i>Date of Electronic Publication: </i>2022 May 12.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101233170 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-7420 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215504131%22">15504131 </searchLink><i>NLM ISO Abbreviation: </i>Cell Metab <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=35561674
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.cmet.2022.04.009
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 857
    Titles:
      – TitleFull: A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Garreta E
      – PersonEntity:
          Name:
            NameFull: Prado P
      – PersonEntity:
          Name:
            NameFull: Stanifer ML
      – PersonEntity:
          Name:
            NameFull: Monteil V
      – PersonEntity:
          Name:
            NameFull: Marco A
      – PersonEntity:
          Name:
            NameFull: Ullate-Agote A
      – PersonEntity:
          Name:
            NameFull: Moya-Rull D
      – PersonEntity:
          Name:
            NameFull: Vilas-Zornoza A
      – PersonEntity:
          Name:
            NameFull: Tarantino C
      – PersonEntity:
          Name:
            NameFull: Romero JP
      – PersonEntity:
          Name:
            NameFull: Jonsson G
      – PersonEntity:
          Name:
            NameFull: Oria R
      – PersonEntity:
          Name:
            NameFull: Leopoldi A
      – PersonEntity:
          Name:
            NameFull: Hagelkruys A
      – PersonEntity:
          Name:
            NameFull: Gallo M
      – PersonEntity:
          Name:
            NameFull: González F
      – PersonEntity:
          Name:
            NameFull: Domingo-Pedrol P
      – PersonEntity:
          Name:
            NameFull: Gavaldà A
      – PersonEntity:
          Name:
            NameFull: Del Pozo CH
      – PersonEntity:
          Name:
            NameFull: Hasan Ali O
      – PersonEntity:
          Name:
            NameFull: Ventura-Aguiar P
      – PersonEntity:
          Name:
            NameFull: Campistol JM
      – PersonEntity:
          Name:
            NameFull: Prosper F
      – PersonEntity:
          Name:
            NameFull: Mirazimi A
      – PersonEntity:
          Name:
            NameFull: Boulant S
      – PersonEntity:
          Name:
            NameFull: Penninger JM
      – PersonEntity:
          Name:
            NameFull: Montserrat N
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 07
              M: 06
              Text: 2022 Jun 07
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1932-7420
          Numbering:
            – Type: volume
              Value: 34
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: Cell metabolism
              Type: main
ResultId 1