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Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways.

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Title: Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways.
Authors: Schaffner SL; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Wassouf Z; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, 37073 Göttingen, Germany.; German Centre for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany., Lazaro DF; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, 37073 Göttingen, Germany., Xylaki M; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, 37073 Göttingen, Germany., Gladish N; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Lin DTS; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., MacIsaac J; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Ramadori K; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Hentrich T; Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076 Tübingen, Germany., Schulze-Hentrich JM; Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076 Tübingen, Germany., Outeiro TF; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, 37073 Göttingen, Germany.; German Centre for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany.; Max Planck Institute for Natural Sciences, 37075 Göttingen, Germany.; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK., Kobor MS; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.
Source: Human molecular genetics [Hum Mol Genet] 2022 Oct 28; Vol. 31 (21), pp. 3694-3714.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways.
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  Data: <searchLink fieldCode="AU" term="%22Schaffner+SL%22">Schaffner SL</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.<br /><searchLink fieldCode="AU" term="%22Wassouf+Z%22">Wassouf Z</searchLink>; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, 37073 Göttingen, Germany.; German Centre for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Lazaro+DF%22">Lazaro DF</searchLink>; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, 37073 Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Xylaki+M%22">Xylaki M</searchLink>; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, 37073 Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Gladish+N%22">Gladish N</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.<br /><searchLink fieldCode="AU" term="%22Lin+DTS%22">Lin DTS</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.<br /><searchLink fieldCode="AU" term="%22MacIsaac+J%22">MacIsaac J</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.<br /><searchLink fieldCode="AU" term="%22Ramadori+K%22">Ramadori K</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.<br /><searchLink fieldCode="AU" term="%22Hentrich+T%22">Hentrich T</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schulze-Hentrich+JM%22">Schulze-Hentrich JM</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076 Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Outeiro+TF%22">Outeiro TF</searchLink>; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, 37073 Göttingen, Germany.; German Centre for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany.; Max Planck Institute for Natural Sciences, 37075 Göttingen, Germany.; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK.<br /><searchLink fieldCode="AU" term="%22Kobor+MS%22">Kobor MS</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22IRL+Press+at+Oxford+University+Press%22">IRL Press at Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9208958 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2083 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209646906%22">09646906 </searchLink><i>NLM ISO Abbreviation: </i>Hum Mol Genet <i>Subsets: </i>MEDLINE
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