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First-in-man, first-in-class phase I study with the monopolar spindle 1 kinase inhibitor S81694 administered intravenously in adult patients with advanced, metastatic solid tumours.

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Title: First-in-man, first-in-class phase I study with the monopolar spindle 1 kinase inhibitor S81694 administered intravenously in adult patients with advanced, metastatic solid tumours.
Authors: Schöffski P; Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium. Electronic address: patrick.schoffski@uzleuven.be., Awada A; Clinical Trials Conduct Unit, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium., de la Bigne AM; TA Oncology, Institut de Recherches Internationales Servier, Suresnes, France., Felloussi Z; TA Oncology, Institut de Recherches Internationales Servier, Suresnes, France., Burbridge M; TA Oncology, Institut de Recherches Internationales Servier, Suresnes, France., Cantero F; TA Oncology, Institut de Recherches Internationales Servier, Suresnes, France., Colombo R; Nerviano Medical Sciences S.r.l., Nerviano, Milan, Italy., Maruzzelli S; Nerviano Medical Sciences S.r.l., Nerviano, Milan, Italy., Ammattatelli K; Nerviano Medical Sciences S.r.l., Nerviano, Milan, Italy., de Jonge M; Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Aftimos P; Clinical Trials Conduct Unit, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium., Dumez H; Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium., Sleijfer S; Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Source: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2022 Jul; Vol. 169, pp. 135-145. Date of Electronic Publication: 2022 May 11.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0852
DOI:10.1016/j.ejca.2022.04.001