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ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.

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Title: ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.
Authors: El-Sayed Moustafa JS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK. julia.el-sayed_moustafa@kcl.ac.uk., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Brotman SM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Guan L; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Villicaña S; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Roberts AL; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Zito A; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, 02114, USA.; Department of Genetics, Harvard Medical School, Boston, MA, 02114, USA., Bonnycastle L; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Erdos MR; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Narisu N; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Welch R; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Yan T; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Lakka T; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland.; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland., Parker S; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Tuomilehto J; University of Helsinki and Department of Medicine, Helsinki University Hospital, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Seow J; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Graham C; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Huettner I; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Acors S; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Kouphou N; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Wadge S; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Duncan EL; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Steves CJ; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Doores KJ; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Malim MH; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Pajukanta P; Department of Human Genetics and Institute for Precision Health, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Koistinen HA; University of Helsinki and Department of Medicine, Helsinki University Hospital, Helsinki, Finland.; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Laakso M; Department of Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Falchi M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Bell JT; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK. kerrin.small@kcl.ac.uk.
Source: International journal of obesity (2005) [Int J Obes (Lond)] 2022 Aug; Vol. 46 (8), pp. 1478-1486. Date of Electronic Publication: 2022 May 20.
Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101256108 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5497 (Electronic) Linking ISSN: 03070565 NLM ISO Abbreviation: Int J Obes (Lond) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.
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Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Welch+R%22">Welch R</searchLink>; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Yan+T%22">Yan T</searchLink>; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lakka+T%22">Lakka T</searchLink>; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland.; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Parker+S%22">Parker S</searchLink>; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Tuomilehto+J%22">Tuomilehto J</searchLink>; 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National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pajukanta+P%22">Pajukanta P</searchLink>; Department of Human Genetics and Institute for Precision Health, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Boehnke+M%22">Boehnke M</searchLink>; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Koistinen+HA%22">Koistinen HA</searchLink>; University of Helsinki and Department of Medicine, Helsinki University Hospital, Helsinki, Finland.; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Laakso+M%22">Laakso M</searchLink>; Department of Medicine, University of Eastern Finland, Kuopio, Finland.; 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