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Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.

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Title: Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.
Authors: Zhu K; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Wang Y; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Sarlus H; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Geng K; Department of Microbiology, Tumor and Cell Biology, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden., Nutma E; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands., Sun J; Department of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai, China.; Shanghai Medical College, Fudan University, Shanghai, China., Kung SY; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Bay C; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Han J; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Min JH; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Benito-Cuesta I; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Lund H; Department of Physiology and Pharmacology, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Amor S; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands., Wang J; Department of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai, China.; Shanghai Medical College, Fudan University, Shanghai, China., Zhang XM; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Kutter C; Department of Microbiology, Tumor and Cell Biology, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden., Guerreiro-Cacais AO; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Högberg B; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Harris RA; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
Source: EMBO reports [EMBO Rep] 2022 Jul 05; Vol. 23 (7), pp. e54499. Date of Electronic Publication: 2022 May 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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