Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.
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| Title: | Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation. |
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| Authors: | Zhu K; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Wang Y; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Sarlus H; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Geng K; Department of Microbiology, Tumor and Cell Biology, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden., Nutma E; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands., Sun J; Department of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai, China.; Shanghai Medical College, Fudan University, Shanghai, China., Kung SY; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Bay C; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Han J; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Min JH; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Benito-Cuesta I; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Lund H; Department of Physiology and Pharmacology, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Amor S; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands., Wang J; Department of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai, China.; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai, China.; Shanghai Medical College, Fudan University, Shanghai, China., Zhang XM; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Kutter C; Department of Microbiology, Tumor and Cell Biology, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden., Guerreiro-Cacais AO; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Högberg B; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Harris RA; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden. |
| Source: | EMBO reports [EMBO Rep] 2022 Jul 05; Vol. 23 (7), pp. e54499. Date of Electronic Publication: 2022 May 20. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1469-3178 |
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| DOI: | 10.15252/embr.202154499 |
