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Humoral and T-Cell Immune Response After 3 Doses of Messenger RNA Severe Acute Respiratory Syndrome Coronavirus 2 Vaccines in Fragile Patients: The Italian VAX4FRAIL Study.

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Title: Humoral and T-Cell Immune Response After 3 Doses of Messenger RNA Severe Acute Respiratory Syndrome Coronavirus 2 Vaccines in Fragile Patients: The Italian VAX4FRAIL Study.
Authors: Corradini P; Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy.; School of Medicine, University of Milan, Milan, Italy., Agrati C; Cellular Immunology Laboratory, National Institute for Infectious Diseases L Spallanzani - IRCCS, Rome, Italy., Apolone G; Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy., Mantovani A; Humanitas Scientific Directorate, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; William Harvey Research Institute, Queen Mary University, London, United Kingdom., Giannarelli D; Biostatistical Unit, Istituto Nazionale Tumori Regina Elena IRCCS - IFO, Rome, Italy., Marasco V; Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy., Bordoni V; Cellular Immunology Laboratory, National Institute for Infectious Diseases L Spallanzani - IRCCS, Rome, Italy., Sacchi A; Cellular Immunology Laboratory, National Institute for Infectious Diseases L Spallanzani - IRCCS, Rome, Italy., Matusali G; Virology Laboratory, National Institute for Infectious Diseases L Spallanzani - IRCCS, Rome, Italy., Salvarani C; Unità di Reumatologia, Azienda USL-IRCCS, Reggio Emilia, Italy.; Unità di Reumatologia, Università degli Studi di Modena e Reggio Emilia, Modena., Zinzani PL; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia 'Seràgnoli', Bologna, Italy.; Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Bologna, Italy., Mantegazza R; Neuromuscular Diseases and Neuroimmunology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Tagliavini F; Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Lupo-Stanghellini MT; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy., Ciceri F; IRCSS San Raffaele Scientific Institute, Milano, Italy., Damian S; Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy., Uccelli A; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) University of Genoa, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Fenoglio D; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Centre of Excellence for Biomedical Research and Department of Internal Medicine, University of Genoa, Genoa, Italy., Silvestris N; Medical Oncology Department, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy.; Department of Biomedical Sciences and Human Oncology, University of Bari 'Aldo Moro', Bari, Italy., Baldanti F; Molecular Virology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Clinical, Surgical, Diagnostics and Pediatric Sciences, University of Pavia, Pavia, Italy., Piaggio G; SAFU Unit IRCCS Regina Elena, National Cancer Institute, Istituti Fisioterapici Ospitalieri (IFO), Rome, Italy., Ciliberto G; National Cancer Institute, Istituti Fisioterapici Ospitalieri (IFO), Rome, Italy., Morrone A; San Gallicano Dermatological Institute IRCCS, Rome, Italy., Locatelli F; Department of Pediatric Hematology and Oncology and Cell and Gene Therapy, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.; Department of Gynecology-Obstetrics and Pediatrics, University 'La Sapienza', Roma, Italy., Sinno V; Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy., Rescigno M; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Mucosal Immunology and Microbiota Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy., Costantini M; Azienda Unità Sanitaria Locale (USL)-IRCCS Reggio Emilia, Reggio Emilia, Italy.
Corporate Authors: VAX4FRAIL Study Group
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2023 Feb 08; Vol. 76 (3), pp. e426-e438.
Publication Type: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Humoral and T-Cell Immune Response After 3 Doses of Messenger RNA Severe Acute Respiratory Syndrome Coronavirus 2 Vaccines in Fragile Patients: The Italian VAX4FRAIL Study.
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  Data: <searchLink fieldCode="AU" term="%22Corradini+P%22">Corradini P</searchLink>; Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy.; School of Medicine, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Agrati+C%22">Agrati C</searchLink>; Cellular Immunology Laboratory, National Institute for Infectious Diseases L Spallanzani - IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Apolone+G%22">Apolone G</searchLink>; Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Mantovani+A%22">Mantovani A</searchLink>; Humanitas Scientific Directorate, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; William Harvey Research Institute, Queen Mary University, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Giannarelli+D%22">Giannarelli D</searchLink>; Biostatistical Unit, Istituto Nazionale Tumori Regina Elena IRCCS - IFO, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Marasco+V%22">Marasco V</searchLink>; Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Bordoni+V%22">Bordoni V</searchLink>; Cellular Immunology Laboratory, National Institute for Infectious Diseases L Spallanzani - IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Sacchi+A%22">Sacchi A</searchLink>; Cellular Immunology Laboratory, National Institute for Infectious Diseases L Spallanzani - IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Matusali+G%22">Matusali G</searchLink>; Virology Laboratory, National Institute for Infectious Diseases L Spallanzani - IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Salvarani+C%22">Salvarani C</searchLink>; Unità di Reumatologia, Azienda USL-IRCCS, Reggio Emilia, Italy.; Unità di Reumatologia, Università degli Studi di Modena e Reggio Emilia, Modena.<br /><searchLink fieldCode="AU" term="%22Zinzani+PL%22">Zinzani PL</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia 'Seràgnoli', Bologna, Italy.; Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Mantegazza+R%22">Mantegazza R</searchLink>; Neuromuscular Diseases and Neuroimmunology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Tagliavini+F%22">Tagliavini F</searchLink>; Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lupo-Stanghellini+MT%22">Lupo-Stanghellini MT</searchLink>; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Ciceri+F%22">Ciceri F</searchLink>; IRCSS San Raffaele Scientific Institute, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Damian+S%22">Damian S</searchLink>; Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Uccelli+A%22">Uccelli A</searchLink>; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) University of Genoa, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Fenoglio+D%22">Fenoglio D</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Centre of Excellence for Biomedical Research and Department of Internal Medicine, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Silvestris+N%22">Silvestris N</searchLink>; Medical Oncology Department, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy.; Department of Biomedical Sciences and Human Oncology, University of Bari 'Aldo Moro', Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Baldanti+F%22">Baldanti F</searchLink>; Molecular Virology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Clinical, Surgical, Diagnostics and Pediatric Sciences, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Piaggio+G%22">Piaggio G</searchLink>; SAFU Unit IRCCS Regina Elena, National Cancer Institute, Istituti Fisioterapici Ospitalieri (IFO), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ciliberto+G%22">Ciliberto G</searchLink>; National Cancer Institute, Istituti Fisioterapici Ospitalieri (IFO), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Morrone+A%22">Morrone A</searchLink>; San Gallicano Dermatological Institute IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Locatelli+F%22">Locatelli F</searchLink>; Department of Pediatric Hematology and Oncology and Cell and Gene Therapy, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.; Department of Gynecology-Obstetrics and Pediatrics, University 'La Sapienza', Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Sinno+V%22">Sinno V</searchLink>; Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Rescigno+M%22">Rescigno M</searchLink>; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Mucosal Immunology and Microbiota Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Costantini+M%22">Costantini M</searchLink>; Azienda Unità Sanitaria Locale (USL)-IRCCS Reggio Emilia, Reggio Emilia, Italy.
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