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Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein.

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Title: Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein.
Authors: Patterson JR; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA. patte401@msu.edu., Hirst WD; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA., Howe JW; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA., Russell CP; Cell and Molecular Biology Department, Grand Valley State University, Allendale, MI, USA., Cole-Strauss A; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA., Kemp CJ; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA., Duffy MF; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA., Lamp J; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA., Umstead A; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA., Kubik M; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA., Stoll AC; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA., Vega IE; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA., Steece-Collier K; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA., Chen Y; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA., Campbell AC; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA., Nezich CL; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA., Glajch KE; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA., Sortwell CE; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA.; Mercy Health Hauenstein Neuroscience Medical Center, Grand Rapids, MI, USA.
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2022 May 24; Vol. 8 (1), pp. 61. Date of Electronic Publication: 2022 May 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE
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  Data: Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein.
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  Data: <searchLink fieldCode="AU" term="%22Patterson+JR%22">Patterson JR</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA. patte401@msu.edu.<br /><searchLink fieldCode="AU" term="%22Hirst+WD%22">Hirst WD</searchLink>; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Howe+JW%22">Howe JW</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Russell+CP%22">Russell CP</searchLink>; Cell and Molecular Biology Department, Grand Valley State University, Allendale, MI, USA.<br /><searchLink fieldCode="AU" term="%22Cole-Strauss+A%22">Cole-Strauss A</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Kemp+CJ%22">Kemp CJ</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Duffy+MF%22">Duffy MF</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Lamp+J%22">Lamp J</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Umstead+A%22">Umstead A</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Kubik+M%22">Kubik M</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Stoll+AC%22">Stoll AC</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.<br /><searchLink fieldCode="AU" term="%22Vega+IE%22">Vega IE</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Steece-Collier+K%22">Steece-Collier K</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Campbell+AC%22">Campbell AC</searchLink>; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nezich+CL%22">Nezich CL</searchLink>; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Glajch+KE%22">Glajch KE</searchLink>; Neurodegenerative Diseases Research Unit, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sortwell+CE%22">Sortwell CE</searchLink>; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, USA.; Neuroscience Program, Michigan State University, East Lansing, MI, USA.; Mercy Health Hauenstein Neuroscience Medical Center, Grand Rapids, MI, USA.
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  Data: <searchLink fieldCode="JN" term="%22101675390%22">NPJ Parkinson's disease</searchLink> [NPJ Parkinsons Dis] 2022 May 24; Vol. 8 (1), pp. 61. <i>Date of Electronic Publication: </i>2022 May 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101675390 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2373-8057 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223738057%22">23738057 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Parkinsons Dis <i>Subsets: </i>PubMed not MEDLINE
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