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Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective.

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Title: Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective.
Authors: Taskar KS; Drug Metabolism and Pharmacokinetics, IVIVT, GlaxoSmithKline, Stevenage, UK., Yang X; Office of Clinical Pharmacology, Center of Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Neuhoff S; Certara UK Ltd., Simcyp Division, Sheffield, UK., Patel M; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA., Yoshida K; Clinical Pharmacology, Genentech Early Research and Development, South San Francisco, California, USA., Paine MF; Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA., Brouwer KLR; Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Chu X; Department of ADME and Discovery Toxicology, Merck & Co., Inc., Kenilworth, New Jersey, USA., Sugiyama Y; Laboratory of Quantitative System PK/Pharmacodynamics, School of Pharmacy, Josai International University, Tokyo, Japan., Cook J; Clinical Pharmacology, Global Product Development, Pfizer Inc., Groton, Connecticut, USA., Polli JW; Global Medical Sciences, ViiV Healthcare, Research Triangle Park, North Carolina, USA., Hanna I; Pharmacokinetic Sciences-Oncology, Novartis Institute for Biomedical Research, East Hanover, New Jersey, USA., Lai Y; Drug Metabolism, Gilead Sciences Inc., Foster City, California, USA., Zamek-Gliszczynski M; Drug Metabolism and Pharmacokinetics, IVIVT, GlaxoSmithKline, Upper Providence, Pennsylvania, USA.
Corporate Authors: ITC
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Sep; Vol. 112 (3), pp. 573-592. Date of Electronic Publication: 2022 Jun 22.
Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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