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Defining mitochondrial protein functions through deep multiomic profiling.

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Title: Defining mitochondrial protein functions through deep multiomic profiling.
Authors: Rensvold JW; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.; Morgridge Institute for Research, Madison, WI, USA., Shishkova E; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Sverchkov Y; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA., Miller IJ; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Cetinkaya A; Department of Medical Genetics, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Pyle A; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Manicki M; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.; Morgridge Institute for Research, Madison, WI, USA., Brademan DR; Morgridge Institute for Research, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Alanay Y; Department of Pediatrics, Pediatric Genetics Unit, Faculty of Medicine, Hacettepe University, Ankara, Turkey.; Department of Pediatrics, Pediatric Genetics Unit, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey., Raiman J; Department of Clinical Inherited Metabolic Disorders, Birmingham Women's and Children's Hospital NHS Trust, Birmingham, UK., Jochem A; Morgridge Institute for Research, Madison, WI, USA., Hutchins PD; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Peters SR; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Linke V; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Overmyer KA; Morgridge Institute for Research, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Salome AZ; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Hebert AS; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Vincent CE; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Kwiecien NW; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Rush MJP; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Westphall MS; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Craven M; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA., Akarsu NA; Department of Medical Genetics, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Taylor RW; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; NHS Highly Specialised Services for Rare Mitochondrial Disorders, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Coon JJ; Morgridge Institute for Research, Madison, WI, USA. jcoon@chem.wisc.edu.; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA. jcoon@chem.wisc.edu.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA. jcoon@chem.wisc.edu.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA. jcoon@chem.wisc.edu., Pagliarini DJ; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Morgridge Institute for Research, Madison, WI, USA. pagliarini@wustl.edu.; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA. pagliarini@wustl.edu.; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA. pagliarini@wustl.edu.
Source: Nature [Nature] 2022 Jun; Vol. 606 (7913), pp. 382-388. Date of Electronic Publication: 2022 May 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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Morgridge Institute for Research, Madison, WI, USA. jcoon@chem.wisc.edu.; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA. jcoon@chem.wisc.edu.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA. jcoon@chem.wisc.edu.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA. jcoon@chem.wisc.edu.<br /><searchLink fieldCode="AU" term="%22Pagliarini+DJ%22">Pagliarini DJ</searchLink>; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Morgridge Institute for Research, Madison, WI, USA. pagliarini@wustl.edu.; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA. pagliarini@wustl.edu.; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; 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