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Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma.

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Title: Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma.
Authors: Swetha M; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram 695011, Kerala, India., Keerthana CK; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram 695011, Kerala, India., Rayginia TP; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram 695011, Kerala, India., Nath LR; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.; Department of Pharmacognosy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Science Campus, Kochi 682041, Kerala, India., Haritha NH; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India., Shabna A; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India., Kalimuthu K; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India., Thangarasu AK; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India., Aiswarya SU; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India., Jannet S; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India., Pillai S; Department of Surgical Oncology, Jubilee Mission Medical College and Research Institute, Thrissur 680005, Kerala, India., Harikumar KB; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India., Sundaram S; Department of Pathology, Government Medical College, Kottayam 686008, Kerala, India., Anto NP; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel., Wu DH; Section of Medical Physics, Department of Radiological Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.; School of Computer Science, Gallogly College of Engineering, University of Oklahoma, Norman, OK 731019, USA.; School of Electrical and Computer Engineering, Gallogly College of Engineering, University of Oklahoma, Norman, OK 731019, USA., Lankalapalli RS; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India., Towner R; Departments of Pathology and Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Isakov N; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel., Deepa SS; Department of Biochemistry and Molecular Biology, and Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Anto RJ; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.
Source: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2022 May 22; Vol. 15 (5). Date of Electronic Publication: 2022 May 22.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238453 Publication Model: Electronic Cited Medium: Print ISSN: 1424-8247 (Print) Linking ISSN: 14248247 NLM ISO Abbreviation: Pharmaceuticals (Basel) Subsets: PubMed not MEDLINE
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  Data: Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Swetha+M%22">Swetha M</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram 695011, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Keerthana+CK%22">Keerthana CK</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram 695011, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Rayginia+TP%22">Rayginia TP</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram 695011, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Nath+LR%22">Nath LR</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.; Department of Pharmacognosy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Science Campus, Kochi 682041, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Haritha+NH%22">Haritha NH</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Shabna+A%22">Shabna A</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Kalimuthu+K%22">Kalimuthu K</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Thangarasu+AK%22">Thangarasu AK</searchLink>; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Aiswarya+SU%22">Aiswarya SU</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Jannet+S%22">Jannet S</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Pillai+S%22">Pillai S</searchLink>; Department of Surgical Oncology, Jubilee Mission Medical College and Research Institute, Thrissur 680005, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Harikumar+KB%22">Harikumar KB</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Sundaram+S%22">Sundaram S</searchLink>; Department of Pathology, Government Medical College, Kottayam 686008, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Anto+NP%22">Anto NP</searchLink>; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel.<br /><searchLink fieldCode="AU" term="%22Wu+DH%22">Wu DH</searchLink>; Section of Medical Physics, Department of Radiological Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.; School of Computer Science, Gallogly College of Engineering, University of Oklahoma, Norman, OK 731019, USA.; School of Electrical and Computer Engineering, Gallogly College of Engineering, University of Oklahoma, Norman, OK 731019, USA.<br /><searchLink fieldCode="AU" term="%22Lankalapalli+RS%22">Lankalapalli RS</searchLink>; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Towner+R%22">Towner R</searchLink>; Departments of Pathology and Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.<br /><searchLink fieldCode="AU" term="%22Isakov+N%22">Isakov N</searchLink>; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel.<br /><searchLink fieldCode="AU" term="%22Deepa+SS%22">Deepa SS</searchLink>; Department of Biochemistry and Molecular Biology, and Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.<br /><searchLink fieldCode="AU" term="%22Anto+RJ%22">Anto RJ</searchLink>; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.
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