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Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma.

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Title: Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma.
Authors: Creaney J; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia., Patch AM; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Addala V; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Sneddon SA; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia., Nones K; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Dick IM; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia., Lee YCG; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia., Newell F; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Rouse EJ; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia., Naeini MM; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Kondrashova O; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Lakis V; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Nakas A; Cancer Research UK Centre Leicester, University of Leicester & University Hospitals of Leicester NHS Trust, Leicester, UK., Waller D; Cancer Research UK Centre Leicester, University of Leicester & University Hospitals of Leicester NHS Trust, Leicester, UK., Sharkey A; Cancer Research UK Centre Leicester, University of Leicester & University Hospitals of Leicester NHS Trust, Leicester, UK., Mukhopadhyay P; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Kazakoff SH; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Koufariotis LT; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Davidson AL; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Ramarao-Milne P; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Holmes O; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Xu Q; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Leonard C; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Wood S; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Grimmond SM; University of Melbourne Centre for Cancer Research, University of Melbourne, Melbourne, VIC, Australia., Bueno R; Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, MA, USA., Fennell DA; Cancer Research UK Centre Leicester, University of Leicester & University Hospitals of Leicester NHS Trust, Leicester, UK., Pearson JV; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia., Robinson BW; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia. bruce.robinson@uwa.edu.au.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia. bruce.robinson@uwa.edu.au.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia. bruce.robinson@uwa.edu.au., Waddell N; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia. nic.waddell@qimrberghofer.edu.au.
Source: Genome medicine [Genome Med] 2022 May 30; Vol. 14 (1), pp. 58. Date of Electronic Publication: 2022 May 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma.
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  Data: <searchLink fieldCode="AU" term="%22Creaney+J%22">Creaney J</searchLink>; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Patch+AM%22">Patch AM</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Addala+V%22">Addala V</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.; 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National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Newell+F%22">Newell F</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Rouse+EJ%22">Rouse EJ</searchLink>; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Naeini+MM%22">Naeini MM</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Kondrashova+O%22">Kondrashova O</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Lakis+V%22">Lakis V</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Nakas+A%22">Nakas A</searchLink>; Cancer Research UK Centre Leicester, University of Leicester & University Hospitals of Leicester NHS Trust, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Waller+D%22">Waller D</searchLink>; Cancer Research UK Centre Leicester, University of Leicester & University Hospitals of Leicester NHS Trust, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Sharkey+A%22">Sharkey A</searchLink>; Cancer Research UK Centre Leicester, University of Leicester & University Hospitals of Leicester NHS Trust, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Mukhopadhyay+P%22">Mukhopadhyay P</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Kazakoff+SH%22">Kazakoff SH</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Koufariotis+LT%22">Koufariotis LT</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Davidson+AL%22">Davidson AL</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Ramarao-Milne+P%22">Ramarao-Milne P</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Holmes+O%22">Holmes O</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Leonard+C%22">Leonard C</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Wood+S%22">Wood S</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Grimmond+SM%22">Grimmond SM</searchLink>; University of Melbourne Centre for Cancer Research, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Bueno+R%22">Bueno R</searchLink>; Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fennell+DA%22">Fennell DA</searchLink>; Cancer Research UK Centre Leicester, University of Leicester & University Hospitals of Leicester NHS Trust, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Pearson+JV%22">Pearson JV</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Robinson+BW%22">Robinson BW</searchLink>; National Centre for Asbestos Related Disease, Medical School, University of Western Australia, Level 5, QQ Block, QEII Medical Centre, 6 Verdun Street, Nedlands, WA, 6009, Australia. bruce.robinson@uwa.edu.au.; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia. bruce.robinson@uwa.edu.au.; Centre for Respiratory Health, University of Western Australia, Nedlands, WA, Australia. bruce.robinson@uwa.edu.au.<br /><searchLink fieldCode="AU" term="%22Waddell+N%22">Waddell N</searchLink>; Medical Genomics, Clinical Genomics and Genome Informatics Groups, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD, 4006, Australia. nic.waddell@qimrberghofer.edu.au.
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