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Targeting mitochondrial DNA polymerase gamma for selective inhibition of MLH1 deficient colon cancer growth.

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Title: Targeting mitochondrial DNA polymerase gamma for selective inhibition of MLH1 deficient colon cancer growth.
Authors: Somuncu B; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey., Ekmekcioglu A; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey., Antmen FM; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey., Ertuzun T; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey., Deniz E; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey., Keskin N; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey., Park J; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America., Yazici IE; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey., Simsek B; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey., Erman B; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Bogazici University, Istanbul, Turkey., Yin W; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America., Erman B; Department of Chemical and Biological Engineering, Koc University, Istanbul, Turkey., Muftuoglu M; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Source: PloS one [PLoS One] 2022 Jun 03; Vol. 17 (6), pp. e0268391. Date of Electronic Publication: 2022 Jun 03 (Print Publication: 2022).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting mitochondrial DNA polymerase gamma for selective inhibition of MLH1 deficient colon cancer growth.
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  Data: <searchLink fieldCode="AU" term="%22Somuncu+B%22">Somuncu B</searchLink>; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Ekmekcioglu+A%22">Ekmekcioglu A</searchLink>; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Antmen+FM%22">Antmen FM</searchLink>; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Ertuzun+T%22">Ertuzun T</searchLink>; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Deniz+E%22">Deniz E</searchLink>; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Keskin+N%22">Keskin N</searchLink>; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Yazici+IE%22">Yazici IE</searchLink>; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Simsek+B%22">Simsek B</searchLink>; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Erman+B%22">Erman B</searchLink>; Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Bogazici University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Yin+W%22">Yin W</searchLink>; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Erman+B%22">Erman B</searchLink>; Department of Chemical and Biological Engineering, Koc University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Muftuoglu+M%22">Muftuoglu M</searchLink>; Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
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