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Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.

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Title: Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.
Authors: Meijer TG; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands. t.meijer@erasmusmc.nl.; Department of Pathology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands. t.meijer@erasmusmc.nl.; Oncode Institute, Utrecht, The Netherlands. t.meijer@erasmusmc.nl., Nguyen L; Oncode Institute, Utrecht, The Netherlands.; Department of Molecular Genetics, University Medical Center Utrecht, Utrecht, The Netherlands., Van Hoeck A; Oncode Institute, Utrecht, The Netherlands.; Department of Molecular Genetics, University Medical Center Utrecht, Utrecht, The Netherlands., Sieuwerts AM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Verkaik NS; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Ladan MM; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Ruigrok-Ritstier K; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., van Deurzen CHM; Department of Pathology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., van de Werken HJG; Cancer Computational Biology Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Immunology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Lips EH; Department of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Linn SC; Department of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Pathology, University Medical Centre Utrecht, Utrecht, The Netherlands., Memari Y; Academic Department of Medical Genetics, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.; MRC Cancer Unit, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Davies H; Academic Department of Medical Genetics, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.; MRC Cancer Unit, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Nik-Zainal S; Academic Department of Medical Genetics, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.; MRC Cancer Unit, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Kanaar R; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Martens JWM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Cuppen E; Oncode Institute, Utrecht, The Netherlands.; Department of Molecular Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.; Science Park, Hartwig Medical Foundation, Amsterdam, The Netherlands., Jager A; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., van Gent DC; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
Source: Oncogene [Oncogene] 2022 Jun; Vol. 41 (26), pp. 3498-3506. Date of Electronic Publication: 2022 Jun 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
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  Data: Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.
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  Data: <searchLink fieldCode="AU" term="%22Meijer+TG%22">Meijer TG</searchLink>; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands. t.meijer@erasmusmc.nl.; Department of Pathology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands. t.meijer@erasmusmc.nl.; Oncode Institute, Utrecht, The Netherlands. t.meijer@erasmusmc.nl.<br /><searchLink fieldCode="AU" term="%22Nguyen+L%22">Nguyen L</searchLink>; Oncode Institute, Utrecht, The Netherlands.; Department of Molecular Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Van+Hoeck+A%22">Van Hoeck A</searchLink>; Oncode Institute, Utrecht, The Netherlands.; Department of Molecular Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sieuwerts+AM%22">Sieuwerts AM</searchLink>; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verkaik+NS%22">Verkaik NS</searchLink>; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ladan+MM%22">Ladan MM</searchLink>; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ruigrok-Ritstier+K%22">Ruigrok-Ritstier K</searchLink>; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Deurzen+CHM%22">van Deurzen CHM</searchLink>; Department of Pathology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+de+Werken+HJG%22">van de Werken HJG</searchLink>; Cancer Computational Biology Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Immunology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lips+EH%22">Lips EH</searchLink>; Department of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Linn+SC%22">Linn SC</searchLink>; Department of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Pathology, University Medical Centre Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Memari+Y%22">Memari Y</searchLink>; Academic Department of Medical Genetics, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.; MRC Cancer Unit, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Davies+H%22">Davies H</searchLink>; Academic Department of Medical Genetics, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.; MRC Cancer Unit, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Nik-Zainal+S%22">Nik-Zainal S</searchLink>; Academic Department of Medical Genetics, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.; MRC Cancer Unit, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kanaar+R%22">Kanaar R</searchLink>; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Martens+JWM%22">Martens JWM</searchLink>; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cuppen+E%22">Cuppen E</searchLink>; Oncode Institute, Utrecht, The Netherlands.; Department of Molecular Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.; Science Park, Hartwig Medical Foundation, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jager+A%22">Jager A</searchLink>; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Gent+DC%22">van Gent DC</searchLink>; Department of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2022 Jun; Vol. 41 (26), pp. 3498-3506. <i>Date of Electronic Publication: </i>2022 Jun 03.
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