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Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative Fluorine Nuclear Magnetic Resonance Spectroscopy: A Novel Approach for Accelerating Drug Development.

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Title: Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative Fluorine Nuclear Magnetic Resonance Spectroscopy: A Novel Approach for Accelerating Drug Development.
Authors: Singh RSP; Pfizer Worldwide Research, Development & Medical, Cambridge, Massachusetts, USA., Walker GS; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA., Kadar EP; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA., Cox LM; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA., Eng H; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA., Sharma R; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA., Bergman AJ; Pfizer Worldwide Research, Development & Medical, Cambridge, Massachusetts, USA., Van Eyck L; Pfizer Clinical Research Unit, Brussels, Belgium., Hackman F; Pfizer Worldwide Research, Development and Medical, Cambridge, UK., Toussi SS; Pfizer Clinical Development, Pearl River, New York, USA., Kalgutkar AS; Pfizer Worldwide Research, Development & Medical, Cambridge, Massachusetts, USA., Obach RS; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Dec; Vol. 112 (6), pp. 1201-1206. Date of Electronic Publication: 2022 Jun 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Metabolism and Excretion of Nirmatrelvir in Humans Using Quantitative Fluorine Nuclear Magnetic Resonance Spectroscopy: A Novel Approach for Accelerating Drug Development.
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  Data: <searchLink fieldCode="AU" term="%22Singh+RSP%22">Singh RSP</searchLink>; Pfizer Worldwide Research, Development & Medical, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Walker+GS%22">Walker GS</searchLink>; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Kadar+EP%22">Kadar EP</searchLink>; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Cox+LM%22">Cox LM</searchLink>; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Eng+H%22">Eng H</searchLink>; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Sharma+R%22">Sharma R</searchLink>; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Bergman+AJ%22">Bergman AJ</searchLink>; Pfizer Worldwide Research, Development & Medical, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Van+Eyck+L%22">Van Eyck L</searchLink>; Pfizer Clinical Research Unit, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Hackman+F%22">Hackman F</searchLink>; Pfizer Worldwide Research, Development and Medical, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Toussi+SS%22">Toussi SS</searchLink>; Pfizer Clinical Development, Pearl River, New York, USA.<br /><searchLink fieldCode="AU" term="%22Kalgutkar+AS%22">Kalgutkar AS</searchLink>; Pfizer Worldwide Research, Development & Medical, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Obach+RS%22">Obach RS</searchLink>; Pfizer Worldwide Research, Development & Medical, Groton, Connecticut, USA.
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  Data: <searchLink fieldCode="JN" term="%220372741%22">Clinical pharmacology and therapeutics</searchLink> [Clin Pharmacol Ther] 2022 Dec; Vol. 112 (6), pp. 1201-1206. <i>Date of Electronic Publication: </i>2022 Jun 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372741 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-6535 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200099236%22">00099236 </searchLink><i>NLM ISO Abbreviation: </i>Clin Pharmacol Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1002/cpt.2683
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              Text: 2022 Dec
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