Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
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| Title: | Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq. |
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| Authors: | Replogle JM; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA 94158, USA; Tetrad Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Saunders RA; Tetrad Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Pogson AN; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Hussmann JA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Lenail A; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Guna A; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Mascibroda L; Department of Biochemistry & Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA., Wagner EJ; Department of Biochemistry & Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA; Department of Biochemistry & Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA., Adelman K; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Lithwick-Yanai G; Ultima Genomics, Newark, CA 94560, USA., Iremadze N; Ultima Genomics, Newark, CA 94560, USA., Oberstrass F; Ultima Genomics, Newark, CA 94560, USA., Lipson D; Ultima Genomics, Newark, CA 94560, USA., Bonnar JL; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Jost M; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA., Norman TM; Program for Computational and Systems Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: normantm@mskcc.org., Weissman JS; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA. Electronic address: weissman@wi.mit.edu. |
| Source: | Cell [Cell] 2022 Jul 07; Vol. 185 (14), pp. 2559-2575.e28. Date of Electronic Publication: 2022 Jun 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 35688146 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Replogle+JM%22">Replogle JM</searchLink>; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA 94158, USA; Tetrad Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Saunders+RA%22">Saunders RA</searchLink>; Tetrad Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Pogson+AN%22">Pogson AN</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Hussmann+JA%22">Hussmann JA</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Lenail+A%22">Lenail A</searchLink>; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Guna+A%22">Guna A</searchLink>; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Mascibroda+L%22">Mascibroda L</searchLink>; Department of Biochemistry & Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Wagner+EJ%22">Wagner EJ</searchLink>; Department of Biochemistry & Molecular Biology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA; Department of Biochemistry & Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.<br /><searchLink fieldCode="AU" term="%22Adelman+K%22">Adelman K</searchLink>; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Lithwick-Yanai+G%22">Lithwick-Yanai G</searchLink>; Ultima Genomics, Newark, CA 94560, USA.<br /><searchLink fieldCode="AU" term="%22Iremadze+N%22">Iremadze N</searchLink>; Ultima Genomics, Newark, CA 94560, USA.<br /><searchLink fieldCode="AU" term="%22Oberstrass+F%22">Oberstrass F</searchLink>; Ultima Genomics, Newark, CA 94560, USA.<br /><searchLink fieldCode="AU" term="%22Lipson+D%22">Lipson D</searchLink>; Ultima Genomics, Newark, CA 94560, USA.<br /><searchLink fieldCode="AU" term="%22Bonnar+JL%22">Bonnar JL</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Jost+M%22">Jost M</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Norman+TM%22">Norman TM</searchLink>; Program for Computational and Systems Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: normantm@mskcc.org.<br /><searchLink fieldCode="AU" term="%22Weissman+JS%22">Weissman JS</searchLink>; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA. Electronic address: weissman@wi.mit.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2022 Jul 07; Vol. 185 (14), pp. 2559-2575.e28. <i>Date of Electronic Publication: </i>2022 Jun 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0413066 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4172 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200928674%22">00928674 </searchLink><i>NLM ISO Abbreviation: </i>Cell <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.cell.2022.05.013 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2559 Titles: – TitleFull: Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Replogle JM – PersonEntity: Name: NameFull: Saunders RA – PersonEntity: Name: NameFull: Pogson AN – PersonEntity: Name: NameFull: Hussmann JA – PersonEntity: Name: NameFull: Lenail A – PersonEntity: Name: NameFull: Guna A – PersonEntity: Name: NameFull: Mascibroda L – PersonEntity: Name: NameFull: Wagner EJ – PersonEntity: Name: NameFull: Adelman K – PersonEntity: Name: NameFull: Lithwick-Yanai G – PersonEntity: Name: NameFull: Iremadze N – PersonEntity: Name: NameFull: Oberstrass F – PersonEntity: Name: NameFull: Lipson D – PersonEntity: Name: NameFull: Bonnar JL – PersonEntity: Name: NameFull: Jost M – PersonEntity: Name: NameFull: Norman TM – PersonEntity: Name: NameFull: Weissman JS IsPartOfRelationships: – BibEntity: Dates: – D: 07 M: 07 Text: 2022 Jul 07 Type: published Y: 2022 Identifiers: – Type: issn-electronic Value: 1097-4172 Numbering: – Type: volume Value: 185 – Type: issue Value: 14 Titles: – TitleFull: Cell Type: main |
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