DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.

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Title: DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
Authors: Muik A; BioNTech SE, Mainz, Germany., Adams 3rd HC; Genmab US Inc, Plainsboro, New Jersey, USA., Gieseke F; BioNTech SE, Mainz, Germany., Altintas I; Translational Research and Precision Medicine, Genmab BV, Utrecht, The Netherlands., Schoedel KB; BioNTech SE, Mainz, Germany., Blum JM; Genmab US Inc, Plainsboro, New Jersey, USA., Sänger B; BioNTech SE, Mainz, Germany., Burm SM; Translational Research and Precision Medicine, Genmab BV, Utrecht, The Netherlands., Stanganello E; TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany., Verzijl D; Translational Research and Precision Medicine, Genmab BV, Utrecht, The Netherlands., Spires VM; Genmab US Inc, Plainsboro, New Jersey, USA., Vascotto F; TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany., Toker A; BioNTech SE, Mainz, Germany., Quinkhardt J; BioNTech SE, Mainz, Germany., Fereshteh M; Genmab US Inc, Plainsboro, New Jersey, USA., Diken M; BioNTech SE, Mainz, Germany., Satijn DPE; Genmab BV, Utrecht, The Netherlands., Kreiter S; BioNTech SE, Mainz, Germany., Ahmadi T; Experimental Medicine, Genmab US Inc, Plainsboro, New Jersey, USA., Breij ECW; Translational Research and Precision Medicine, Genmab BV, Utrecht, The Netherlands., Türeci Ö; BioNTech SE, Mainz, Germany., Sasser K; Genmab US Inc, Plainsboro, New Jersey, USA., Sahin U; BioNTech SE, Mainz, Germany.; TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany., Jure-Kunkel M; Genmab US Inc, Plainsboro, New Jersey, USA mjk@genmab.com.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2022 Jun; Vol. 10 (6).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 35688554
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PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
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  Data: <searchLink fieldCode="AU" term="%22Muik+A%22">Muik A</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Adams+3rd+HC%22">Adams 3rd HC</searchLink>; Genmab US Inc, Plainsboro, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Gieseke+F%22">Gieseke F</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Altintas+I%22">Altintas I</searchLink>; Translational Research and Precision Medicine, Genmab BV, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schoedel+KB%22">Schoedel KB</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Blum+JM%22">Blum JM</searchLink>; Genmab US Inc, Plainsboro, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Sänger+B%22">Sänger B</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Burm+SM%22">Burm SM</searchLink>; Translational Research and Precision Medicine, Genmab BV, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Stanganello+E%22">Stanganello E</searchLink>; TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Verzijl+D%22">Verzijl D</searchLink>; Translational Research and Precision Medicine, Genmab BV, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Spires+VM%22">Spires VM</searchLink>; Genmab US Inc, Plainsboro, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Vascotto+F%22">Vascotto F</searchLink>; TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Toker+A%22">Toker A</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Quinkhardt+J%22">Quinkhardt J</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Fereshteh+M%22">Fereshteh M</searchLink>; Genmab US Inc, Plainsboro, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Diken+M%22">Diken M</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Satijn+DPE%22">Satijn DPE</searchLink>; Genmab BV, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kreiter+S%22">Kreiter S</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Ahmadi+T%22">Ahmadi T</searchLink>; Experimental Medicine, Genmab US Inc, Plainsboro, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Breij+ECW%22">Breij ECW</searchLink>; Translational Research and Precision Medicine, Genmab BV, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Türeci+Ö%22">Türeci Ö</searchLink>; BioNTech SE, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Sasser+K%22">Sasser K</searchLink>; Genmab US Inc, Plainsboro, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Sahin+U%22">Sahin U</searchLink>; BioNTech SE, Mainz, Germany.; TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Jure-Kunkel+M%22">Jure-Kunkel M</searchLink>; Genmab US Inc, Plainsboro, New Jersey, USA mjk@genmab.com.
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  Data: <searchLink fieldCode="JN" term="%22101620585%22">Journal for immunotherapy of cancer</searchLink> [J Immunother Cancer] 2022 Jun; Vol. 10 (6).
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ+Publishing+Group+Ltd%22">BMJ Publishing Group Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101620585 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-1426 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220511426%22">20511426 </searchLink><i>NLM ISO Abbreviation: </i>J Immunother Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1136/jitc-2021-004322
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      – Code: eng
        Text: English
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      – TitleFull: DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
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              Text: 2022 Jun
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