A ten-gene DNA-damage response pathway gene expression signature predicts gemtuzumab ozogamicin response in pediatric AML patients treated on COGAAML0531 and AAML03P1 trials.

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Title: A ten-gene DNA-damage response pathway gene expression signature predicts gemtuzumab ozogamicin response in pediatric AML patients treated on COGAAML0531 and AAML03P1 trials.
Authors: Gbadamosi MO; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Shastri VM; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Elsayed AH; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Ries R; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Olabige O; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Nguyen NHK; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., De Jesus A; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Wang YC; COG Statistics and Data Center, Monrovia, CA, USA., Dang A; COG Statistics and Data Center, Monrovia, CA, USA., Hirsch BA; University of Minnesota, Minneapolis, MN, USA., Alonzo TA; COG Statistics and Data Center, Monrovia, CA, USA.; Biostatistics Division, University of Southern California, Los Angeles, CA, USA., Gamis A; Department of Hematology-Oncology, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA., Meshinchi S; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Lamba JK; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA. jlamba@cop.ufl.edu.; Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL, USA. jlamba@cop.ufl.edu.
Source: Leukemia [Leukemia] 2022 Aug; Vol. 36 (8), pp. 2022-2031. Date of Electronic Publication: 2022 Jun 10.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A ten-gene DNA-damage response pathway gene expression signature predicts gemtuzumab ozogamicin response in pediatric AML patients treated on COGAAML0531 and AAML03P1 trials.
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  Data: <searchLink fieldCode="AU" term="%22Gbadamosi+MO%22">Gbadamosi MO</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Shastri+VM%22">Shastri VM</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Elsayed+AH%22">Elsayed AH</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ries+R%22">Ries R</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Olabige+O%22">Olabige O</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+NHK%22">Nguyen NHK</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22De+Jesus+A%22">De Jesus A</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wang+YC%22">Wang YC</searchLink>; COG Statistics and Data Center, Monrovia, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dang+A%22">Dang A</searchLink>; COG Statistics and Data Center, Monrovia, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hirsch+BA%22">Hirsch BA</searchLink>; University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Alonzo+TA%22">Alonzo TA</searchLink>; COG Statistics and Data Center, Monrovia, CA, USA.; Biostatistics Division, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gamis+A%22">Gamis A</searchLink>; Department of Hematology-Oncology, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Meshinchi+S%22">Meshinchi S</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Lamba+JK%22">Lamba JK</searchLink>; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA. jlamba@cop.ufl.edu.; Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL, USA. jlamba@cop.ufl.edu.
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  Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2022 Aug; Vol. 36 (8), pp. 2022-2031. <i>Date of Electronic Publication: </i>2022 Jun 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE
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