NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
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| Title: | NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. |
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| Authors: | Gleixner AM; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Verdone BM; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA., Otte CG; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Physician Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Anderson EN; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Ramesh N; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA., Shapiro OR; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Gale JR; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Mauna JC; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Mann JR; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA., Copley KE; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Daley EL; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA., Ortega JA; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA., Cicardi ME; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA., Kiskinis E; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA.; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Kofler J; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA., Pandey UB; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA., Trotti D; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA., Donnelly CJ; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. cjdon25@pitt.edu.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA. cjdon25@pitt.edu.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA. cjdon25@pitt.edu. |
| Source: | Nature communications [Nat Commun] 2022 Jun 13; Vol. 13 (1), pp. 3380. Date of Electronic Publication: 2022 Jun 13. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-022-31098-6 |
