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NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.

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Title: NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
Authors: Gleixner AM; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Verdone BM; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA., Otte CG; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Physician Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Anderson EN; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Ramesh N; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA., Shapiro OR; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Gale JR; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Mauna JC; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Mann JR; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA., Copley KE; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA., Daley EL; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA., Ortega JA; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA., Cicardi ME; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA., Kiskinis E; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA.; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Kofler J; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA., Pandey UB; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA., Trotti D; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA., Donnelly CJ; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. cjdon25@pitt.edu.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA. cjdon25@pitt.edu.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA. cjdon25@pitt.edu.
Source: Nature communications [Nat Commun] 2022 Jun 13; Vol. 13 (1), pp. 3380. Date of Electronic Publication: 2022 Jun 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
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  Data: <searchLink fieldCode="AU" term="%22Gleixner+AM%22">Gleixner AM</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Verdone+BM%22">Verdone BM</searchLink>; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Otte+CG%22">Otte CG</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Physician Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+EN%22">Anderson EN</searchLink>; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ramesh+N%22">Ramesh N</searchLink>; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shapiro+OR%22">Shapiro OR</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gale+JR%22">Gale JR</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mauna+JC%22">Mauna JC</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mann+JR%22">Mann JR</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Copley+KE%22">Copley KE</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Daley+EL%22">Daley EL</searchLink>; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ortega+JA%22">Ortega JA</searchLink>; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Cicardi+ME%22">Cicardi ME</searchLink>; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kiskinis+E%22">Kiskinis E</searchLink>; The Ken & Ruth Davee Department of Neurology, Northwestern University of Feinberg School of Medicine, Chicago, IL, USA.; Department of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Kofler+J%22">Kofler J</searchLink>; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pandey+UB%22">Pandey UB</searchLink>; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Trotti+D%22">Trotti D</searchLink>; Department of Neuroscience, Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Donnelly+CJ%22">Donnelly CJ</searchLink>; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. cjdon25@pitt.edu.; LiveLikeLou Center for ALS Research, University of Pittsburgh Brain Institute, Pittsburgh, PA, USA. cjdon25@pitt.edu.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA. cjdon25@pitt.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Jun 13; Vol. 13 (1), pp. 3380. <i>Date of Electronic Publication: </i>2022 Jun 13.
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