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Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes.

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Title: Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes.
Authors: Bustoros M; Medical Oncology, Dana-Farber Cancer Center, Boston, MA, USA.; Division of Hematology & Medical Oncology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Anand S; Broad Institute of MIT & Harvard, Cambridge, MA, USA.; Boston University School of Medicine, Boston, MA, USA., Sklavenitis-Pistofidis R; Medical Oncology, Dana-Farber Cancer Center, Boston, MA, USA.; Broad Institute of MIT & Harvard, Cambridge, MA, USA., Redd R; Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Boyle EM; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA., Zhitomirsky B; Broad Institute of MIT & Harvard, Cambridge, MA, USA., Dunford AJ; Broad Institute of MIT & Harvard, Cambridge, MA, USA., Tai YT; Medical Oncology, Dana-Farber Cancer Center, Boston, MA, USA., Chavda SJ; Division of Hematology, University College London, London, UK., Boehner C; Medical Oncology, Dana-Farber Cancer Center, Boston, MA, USA., Neuse CJ; Medical Oncology, Dana-Farber Cancer Center, Boston, MA, USA.; University of Münster Medical School, Münster, Germany., Rahmat M; Medical Oncology, Dana-Farber Cancer Center, Boston, MA, USA., Dutta A; Medical Oncology, Dana-Farber Cancer Center, Boston, MA, USA., Casneuf T; Janssen Research and Development, Beerse, Belgium., Verona R; Janssen Research and Development, Spring House, PA, USA., Kastritis E; Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece., Trippa L; Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Stewart C; Broad Institute of MIT & Harvard, Cambridge, MA, USA., Walker BA; Melvin and Bren Simon Comprehensive Cancer Center, Indiana University, Indianapolis, IN, USA., Davies FE; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA., Dimopoulos MA; Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece., Bergsagel PL; Division of Hematology, Mayo Clinic, Scottsdale, AZ, USA., Yong K; Division of Hematology, University College London, London, UK., Morgan GJ; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA., Aguet F; Broad Institute of MIT & Harvard, Cambridge, MA, USA., Getz G; Broad Institute of MIT & Harvard, Cambridge, MA, USA. gadgetz@broadinstitute.org.; Department of Pathology, Massachusetts General Hospital Cancer Center, Boston, MA, USA. gadgetz@broadinstitute.org., Ghobrial IM; Medical Oncology, Dana-Farber Cancer Center, Boston, MA, USA. Irene_Ghobrial@dfci.harvard.edu.; Broad Institute of MIT & Harvard, Cambridge, MA, USA. Irene_Ghobrial@dfci.harvard.edu.
Source: Nature communications [Nat Commun] 2022 Jun 15; Vol. 13 (1), pp. 3449. Date of Electronic Publication: 2022 Jun 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes.
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