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Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction.

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Title: Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction.
Authors: Mahmud Z; Department of Biochemistry, University of Alberta, Edmonton, AB, Canada., Tikunova S; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States., Belevych N; Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, United States., Wagg CS; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada., Zhabyeyev P; Department of Medicine, University of Alberta, Edmonton, AB, Canada., Liu PB; Department of Medicine, University of Alberta, Edmonton, AB, Canada., Rasicci DV; Department of Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, University Park, PA, United States., Yengo CM; Department of Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, University Park, PA, United States., Oudit GY; Department of Medicine, University of Alberta, Edmonton, AB, Canada., Lopaschuk GD; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada., Reiser PJ; Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, United States., Davis JP; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States., Hwang PM; Department of Biochemistry, University of Alberta, Edmonton, AB, Canada.; Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Source: Frontiers in physiology [Front Physiol] 2022 Jun 08; Vol. 13, pp. 892979. Date of Electronic Publication: 2022 Jun 08 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101549006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-042X (Print) Linking ISSN: 1664042X NLM ISO Abbreviation: Front Physiol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction.
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  Data: <searchLink fieldCode="AU" term="%22Mahmud+Z%22">Mahmud Z</searchLink>; Department of Biochemistry, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Tikunova+S%22">Tikunova S</searchLink>; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Belevych+N%22">Belevych N</searchLink>; Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Wagg+CS%22">Wagg CS</searchLink>; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Zhabyeyev+P%22">Zhabyeyev P</searchLink>; Department of Medicine, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Liu+PB%22">Liu PB</searchLink>; Department of Medicine, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Rasicci+DV%22">Rasicci DV</searchLink>; Department of Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, University Park, PA, United States.<br /><searchLink fieldCode="AU" term="%22Yengo+CM%22">Yengo CM</searchLink>; Department of Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, University Park, PA, United States.<br /><searchLink fieldCode="AU" term="%22Oudit+GY%22">Oudit GY</searchLink>; Department of Medicine, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Lopaschuk+GD%22">Lopaschuk GD</searchLink>; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Reiser+PJ%22">Reiser PJ</searchLink>; Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Davis+JP%22">Davis JP</searchLink>; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Hwang+PM%22">Hwang PM</searchLink>; Department of Biochemistry, University of Alberta, Edmonton, AB, Canada.; Department of Medicine, University of Alberta, Edmonton, AB, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101549006%22">Frontiers in physiology</searchLink> [Front Physiol] 2022 Jun 08; Vol. 13, pp. 892979. <i>Date of Electronic Publication: </i>2022 Jun 08 (<i>Print Publication: </i>2022).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101549006 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-042X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221664042X%22">1664042X </searchLink><i>NLM ISO Abbreviation: </i>Front Physiol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fphys.2022.892979
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