Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach.
Saved in:
| Title: | Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach. |
|---|---|
| Authors: | Doran AC; Medicine Design - ADME Sciences, Pfizer, United States angela.c.doran@pfizer.com., Burchett W; Pfizer Inc., United States., Landers C; Pfizer Inc., United States., Gualtieri GM; Pfizer Inc., United States., Balesano A; Pfizer Inc., United States., Eng H; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, United States., Dantonio AL; Pfizer, United States., Goosen TC; Pharmacokinetics, Dynamics & Metabolism, Pfizer, Inc, United States., Obach RS; Groton Laboratories, Pfizer Inc., United States. |
| Source: | Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2022 Jul 01; Vol. 50 (9). Date of Electronic Publication: 2022 Jul 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE; PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1521-009X |
|---|---|
| DOI: | 10.1124/dmd.122.000884 |
