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Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach.

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Title: Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach.
Authors: Doran AC; Medicine Design - ADME Sciences, Pfizer, United States angela.c.doran@pfizer.com., Burchett W; Pfizer Inc., United States., Landers C; Pfizer Inc., United States., Gualtieri GM; Pfizer Inc., United States., Balesano A; Pfizer Inc., United States., Eng H; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, United States., Dantonio AL; Pfizer, United States., Goosen TC; Pharmacokinetics, Dynamics & Metabolism, Pfizer, Inc, United States., Obach RS; Groton Laboratories, Pfizer Inc., United States.
Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2022 Jul 01; Vol. 50 (9). Date of Electronic Publication: 2022 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach.
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  Data: <searchLink fieldCode="JN" term="%229421550%22">Drug metabolism and disposition: the biological fate of chemicals</searchLink> [Drug Metab Dispos] 2022 Jul 01; Vol. 50 (9). <i>Date of Electronic Publication: </i>2022 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9421550 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-009X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200909556%22">00909556 </searchLink><i>NLM ISO Abbreviation: </i>Drug Metab Dispos <i>Subsets: </i>MEDLINE; PubMed not MEDLINE
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        Value: 10.1124/dmd.122.000884
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        Text: English
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              M: 07
              Text: 2022 Jul 01
              Type: published
              Y: 2022
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