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Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.

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Title: Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
Authors: Strohm L; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany., Hu Z; Department of Biology, University of Fribourg, Fribourg, Switzerland., Suk Y; Institute for Molecular Physiology, Johannes Gutenberg-University Mainz, Mainz, Germany., Rühmkorf A; Max Planck Institute of Neurobiology, Martinsried, Germany., Sternburg E; Institute for Molecular Physiology, Johannes Gutenberg-University Mainz, Mainz, Germany., Gattringer V; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany., Riemenschneider H; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany.; German Center for Neurodegenerative Diseases Munich, Munich, Germany., Berutti R; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany., Graf E; Institut für Humangenetik, Klinikum Rechts der Isar der Technischen Universität München, Munich, Germany., Weishaupt JH; Division of Neurodegenerative Disorders, Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neurosciences, Heidelberg University, Mannheim, Germany., Brill MS, Harbauer AB; Institute of Neuronal Cell Biology, Technical University of Munich, Munich, Germany.; Max Planck Institute of Neurobiology, Martinsried, Germany.; Munich Cluster for Systems Neurology, Munich, Germany., Dormann D; Institute for Molecular Physiology, Johannes Gutenberg-University Mainz, Mainz, Germany.; Institute of Molecule Biology, Mainz, Germany., Dengjel J; Department of Biology, University of Fribourg, Fribourg, Switzerland., Edbauer D; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany.; German Center for Neurodegenerative Diseases Munich, Munich, Germany., Behrends C; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany christian.behrends@mail03.med.uni-muenchen.de.
Source: Life science alliance [Life Sci Alliance] 2022 Jul 01; Vol. 5 (11). Date of Electronic Publication: 2022 Jul 01 (Print Publication: 2022).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE
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  Data: Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
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  Data: <searchLink fieldCode="AU" term="%22Strohm+L%22">Strohm L</searchLink>; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hu+Z%22">Hu Z</searchLink>; Department of Biology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Suk+Y%22">Suk Y</searchLink>; Institute for Molecular Physiology, Johannes Gutenberg-University Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Rühmkorf+A%22">Rühmkorf A</searchLink>; Max Planck Institute of Neurobiology, Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Sternburg+E%22">Sternburg E</searchLink>; Institute for Molecular Physiology, Johannes Gutenberg-University Mainz, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Gattringer+V%22">Gattringer V</searchLink>; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Riemenschneider+H%22">Riemenschneider H</searchLink>; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany.; German Center for Neurodegenerative Diseases Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Berutti+R%22">Berutti R</searchLink>; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Graf+E%22">Graf E</searchLink>; Institut für Humangenetik, Klinikum Rechts der Isar der Technischen Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Weishaupt+JH%22">Weishaupt JH</searchLink>; Division of Neurodegenerative Disorders, Department of Neurology, Medical Faculty Mannheim, Mannheim Center for Translational Neurosciences, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Brill+MS%22">Brill MS</searchLink><br /><searchLink fieldCode="AU" term="%22Harbauer+AB%22">Harbauer AB</searchLink>; Institute of Neuronal Cell Biology, Technical University of Munich, Munich, Germany.; Max Planck Institute of Neurobiology, Martinsried, Germany.; Munich Cluster for Systems Neurology, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Dormann+D%22">Dormann D</searchLink>; Institute for Molecular Physiology, Johannes Gutenberg-University Mainz, Mainz, Germany.; Institute of Molecule Biology, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Dengjel+J%22">Dengjel J</searchLink>; Department of Biology, University of Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Edbauer+D%22">Edbauer D</searchLink>; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany.; German Center for Neurodegenerative Diseases Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Behrends+C%22">Behrends C</searchLink>; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-University München, Munich, Germany christian.behrends@mail03.med.uni-muenchen.de.
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