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The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study.

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Title: The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study.
Authors: Borges MC; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK., Haycock P; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK., Zheng J; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK., Hemani G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK., Howe LJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK., Schmidt AF; Faculty of Population Health Sciences, Institute of Cardiovascular Science, University College London, London WC1E 6DD, UK.; Department of Cardiology, Division Heart and Lungs, UMC Utrecht, Utrecht 3584 CX, The Netherlands., Staley JR; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK., Lumbers RT; Institute of Health Informatics, University College London, London NW1 2DA, UK.; Health Data Research UK London, University College London NW1 2DA, UK.; UCL British Heart Foundation Research Accelerator, London NW1 2DA, UK., Henry A; Faculty of Population Health Sciences, Institute of Cardiovascular Science, University College London, London WC1E 6DD, UK.; Institute of Health Informatics, University College London, London NW1 2DA, UK.; UCL British Heart Foundation Research Accelerator, London NW1 2DA, UK., Lemaitre RN; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA WA 98101, USA., Gaunt TR; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK., Holmes MV; Medical Research Council Population Health Research Unit, University of Oxford, Oxford OX3 7LF, UK.; Clinical Trial Service and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Davey Smith G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK., Hingorani AD; Faculty of Population Health Sciences, Institute of Cardiovascular Science, University College London, London WC1E 6DD, UK.; Health Data Research UK London, University College London NW1 2DA, UK.; UCL British Heart Foundation Research Accelerator, London NW1 2DA, UK., Lawlor DA; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.; NIHR Bristol Biomedical Research Centre, Bristol BS8 2BN, UK.
Source: Human molecular genetics [Hum Mol Genet] 2022 Nov 28; Vol. 31 (23), pp. 4034-4054.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study.
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  Data: <searchLink fieldCode="AU" term="%22Borges+MC%22">Borges MC</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.<br /><searchLink fieldCode="AU" term="%22Haycock+P%22">Haycock P</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.<br /><searchLink fieldCode="AU" term="%22Zheng+J%22">Zheng J</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.<br /><searchLink fieldCode="AU" term="%22Hemani+G%22">Hemani G</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.<br /><searchLink fieldCode="AU" term="%22Howe+LJ%22">Howe LJ</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.<br /><searchLink fieldCode="AU" term="%22Schmidt+AF%22">Schmidt AF</searchLink>; Faculty of Population Health Sciences, Institute of Cardiovascular Science, University College London, London WC1E 6DD, UK.; Department of Cardiology, Division Heart and Lungs, UMC Utrecht, Utrecht 3584 CX, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Staley+JR%22">Staley JR</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.<br /><searchLink fieldCode="AU" term="%22Lumbers+RT%22">Lumbers RT</searchLink>; Institute of Health Informatics, University College London, London NW1 2DA, UK.; Health Data Research UK London, University College London NW1 2DA, UK.; UCL British Heart Foundation Research Accelerator, London NW1 2DA, UK.<br /><searchLink fieldCode="AU" term="%22Henry+A%22">Henry A</searchLink>; Faculty of Population Health Sciences, Institute of Cardiovascular Science, University College London, London WC1E 6DD, UK.; Institute of Health Informatics, University College London, London NW1 2DA, UK.; UCL British Heart Foundation Research Accelerator, London NW1 2DA, UK.<br /><searchLink fieldCode="AU" term="%22Lemaitre+RN%22">Lemaitre RN</searchLink>; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Gaunt+TR%22">Gaunt TR</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.<br /><searchLink fieldCode="AU" term="%22Holmes+MV%22">Holmes MV</searchLink>; Medical Research Council Population Health Research Unit, University of Oxford, Oxford OX3 7LF, UK.; Clinical Trial Service and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.<br /><searchLink fieldCode="AU" term="%22Davey+Smith+G%22">Davey Smith G</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.<br /><searchLink fieldCode="AU" term="%22Hingorani+AD%22">Hingorani AD</searchLink>; Faculty of Population Health Sciences, Institute of Cardiovascular Science, University College London, London WC1E 6DD, UK.; Health Data Research UK London, University College London NW1 2DA, UK.; UCL British Heart Foundation Research Accelerator, London NW1 2DA, UK.<br /><searchLink fieldCode="AU" term="%22Lawlor+DA%22">Lawlor DA</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2PN, UK.; NIHR Bristol Biomedical Research Centre, Bristol BS8 2BN, UK.
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