Screening an In-House Isoquinoline Alkaloids Library for New Blockers of Voltage-Gated Na+ Channels Using Voltage Sensor Fluorescent Probes: Hits and Biases.

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Title:	Screening an In-House Isoquinoline Alkaloids Library for New Blockers of Voltage-Gated Na⁺ Channels Using Voltage Sensor Fluorescent Probes: Hits and Biases.
Authors:	Coquerel Q; Univ Angers, INSERM, CNRS, MITOVASC, Equipe CarME, SFR ICAT, 49000 Angers, France., Legendre C; Univ Angers, INSERM, CNRS, MITOVASC, Equipe CarME, SFR ICAT, 49000 Angers, France., Frangieh J; Univ Angers, INSERM, CNRS, MITOVASC, Equipe CarME, SFR ICAT, 49000 Angers, France.; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, 44000 Nantes, France., Waard S; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, 44000 Nantes, France., Montnach J; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, 44000 Nantes, France., Cmarko L; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, 44000 Nantes, France.; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, 128 00 Prague, Czech Republic.; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 166 10 Prague, Czech Republic., Khoury J; Univ Angers, INSERM, CNRS, MITOVASC, Equipe CarME, SFR ICAT, 49000 Angers, France.; Laboratory of Applied Biotechnology, AZM Centre for Research in Biotechnology and Its Application, Doctoral School for Sciences and Technology, Tripoli 1352, Lebanon., Hassane CS; Univ Angers, INSERM, CNRS, MITOVASC, Equipe CarME, SFR ICAT, 49000 Angers, France.; Univ Angers, SONAS, SFR QUASAV, 49100 Angers, France., Bréard D; Univ Angers, SONAS, SFR QUASAV, 49100 Angers, France., Siegler B; Univ Angers, SONAS, SFR QUASAV, 49100 Angers, France., Fajloun Z; Laboratory of Applied Biotechnology, AZM Centre for Research in Biotechnology and Its Application, Doctoral School for Sciences and Technology, Tripoli 1352, Lebanon., De Pomyers H; Latoxan Laboratory, 26800 Portes lès Valence, France., Mabrouk K; CNRS, ICR, Aix Marseille Univ, 13397 Marseille, France., Weiss N; Department of Pathophysiology, First Faculty of Medicine, Charles University, 160 00 Prague, Czech Republic., Henrion D; Univ Angers, INSERM, CNRS, MITOVASC, Equipe CarME, SFR ICAT, 49000 Angers, France., Richomme P; Univ Angers, SONAS, SFR QUASAV, 49100 Angers, France., Mattei C; Univ Angers, INSERM, CNRS, MITOVASC, Equipe CarME, SFR ICAT, 49000 Angers, France., Waard M; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, 44000 Nantes, France., Le Ray AM; Univ Angers, SONAS, SFR QUASAV, 49100 Angers, France., Legros C; Univ Angers, INSERM, CNRS, MITOVASC, Equipe CarME, SFR ICAT, 49000 Angers, France.
Source:	Molecules (Basel, Switzerland) [Molecules] 2022 Jun 28; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 28.
Publication Type:	Journal Article
Journal Info:	Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
Database:	MEDLINE Ultimate

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ISSN:	1420-3049
DOI:	10.3390/molecules27134133