Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.

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Title: Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.
Authors: Titus HE; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Xu H; Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Robinson AP; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Patel PA; Quantitative Data Science Core Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Chen Y; Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Fantini D; Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Eaton V; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Karl M; Department of Anatomy and Cell Biology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA., Garrison ED; Department of Anatomy and Cell Biology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA., Rose IVL; Neuroscience Institute and Departments of Neuroscience, & Physiology, and Ophthalmology, New York University Grossman School of Medicine, New York, New York, USA., Chiang MY; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Podojil JR; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.; Cour Pharmaceutical Development Company, Northbrook, Illinois, USA., Balabanov R; Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Liddelow SA; Neuroscience Institute and Departments of Neuroscience, & Physiology, and Ophthalmology, New York University Grossman School of Medicine, New York, New York, USA., Miller RH; Department of Anatomy and Cell Biology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA., Popko B; Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Miller SD; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Source: Glia [Glia] 2022 Oct; Vol. 70 (10), pp. 1950-1970. Date of Electronic Publication: 2022 Jul 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8806785 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1136 (Electronic) Linking ISSN: 08941491 NLM ISO Abbreviation: Glia Subsets: MEDLINE
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  Data: Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Titus+HE%22">Titus HE</searchLink>; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+AP%22">Robinson AP</searchLink>; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Patel+PA%22">Patel PA</searchLink>; Quantitative Data Science Core Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Fantini+D%22">Fantini D</searchLink>; Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Eaton+V%22">Eaton V</searchLink>; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Karl+M%22">Karl M</searchLink>; Department of Anatomy and Cell Biology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.<br /><searchLink fieldCode="AU" term="%22Garrison+ED%22">Garrison ED</searchLink>; Department of Anatomy and Cell Biology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.<br /><searchLink fieldCode="AU" term="%22Rose+IVL%22">Rose IVL</searchLink>; Neuroscience Institute and Departments of Neuroscience, & Physiology, and Ophthalmology, New York University Grossman School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Chiang+MY%22">Chiang MY</searchLink>; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Podojil+JR%22">Podojil JR</searchLink>; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.; Cour Pharmaceutical Development Company, Northbrook, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Balabanov+R%22">Balabanov R</searchLink>; Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Liddelow+SA%22">Liddelow SA</searchLink>; Neuroscience Institute and Departments of Neuroscience, & Physiology, and Ophthalmology, New York University Grossman School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Miller+RH%22">Miller RH</searchLink>; Department of Anatomy and Cell Biology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.<br /><searchLink fieldCode="AU" term="%22Popko+B%22">Popko B</searchLink>; Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Miller+SD%22">Miller SD</searchLink>; Department of Microbiology-Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
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  Data: <searchLink fieldCode="JN" term="%228806785%22">Glia</searchLink> [Glia] 2022 Oct; Vol. 70 (10), pp. 1950-1970. <i>Date of Electronic Publication: </i>2022 Jul 09.
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        Value: 10.1002/glia.24231
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        StartPage: 1950
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      – TitleFull: Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.
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              Text: 2022 Oct
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