Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial.
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| Title: | Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. |
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| Authors: | Fischer U; Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland. Electronic address: urs.fischer@usb.ch., Kaesmacher J; University Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Strbian D; Department of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Eker O; Department of Neuroradiology, Hospices Civils de Lyon, Lyon, France., Cognard C; Department of Diagnostic and Therapeutic Neuroradiology, Centre Hospitalier Universitaire de Toulouse, Toulouse, France., Plattner PS; Neuro Clinical Trial Unit, Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Bütikofer L; CTU Bern, University of Bern, Bern, Switzerland., Mordasini P; University Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Deppeler S; Neuro Clinical Trial Unit, Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Pereira VM; Division of Neurosurgery, Department of Surgery and Medical Imaging, St Michael's Hospital, University of Toronto, Toronto, ON, Canada., Albucher JF; Department of Neurology, Centre Hospitalier Universitaire de Toulouse, Toulouse, France., Darcourt J; Department of Diagnostic and Therapeutic Neuroradiology, Centre Hospitalier Universitaire de Toulouse, Toulouse, France., Bourcier R; Department of Diagnostic and Interventional Neuroradiology, Centre Hospitalier Universitaire de Nantes, Nantes Université, Nantes, France., Benoit G; Department of Neurology, Centre Hospitalier Universitaire de Nantes, Nantes Université, Nantes, France., Papagiannaki C; Department of Radiology, CHU Rouen, Rouen, France., Ozkul-Wermester O; Department of Neurology, CHU Rouen, Rouen, France., Sibolt G; Department of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Tiainen M; Department of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Gory B; Department of Diagnostic and Therapeutic Neuroradiology, INSERM U1254, CHRU-Nancy, Université de Lorraine, Nancy, France., Richard S; Department of Neurology, Stroke Unit, INSERM U1116, CHRU-Nancy, Université de Lorraine, Nancy, France., Liman J; Department of Neurology, University Medical Center Goettingen, Goettingen, Germany., Ernst MS; Department of Neuroradiology, University Medical Center Goettingen, Goettingen, Germany., Boulanger M; Department of Neurology, CHU Caen Normandie, University Caen Normandie, INSERM U1237, Caen, France., Barbier C; Department of Neuroradiology, CHU Caen Normandie, University Caen Normandie, INSERM U1237, Caen, France., Mechtouff L; Department of Vascular Neurology, Hospices Civils de Lyon, Lyon, France., Zhang L; Department of Neurology, St George's University Hospital NHS Foundation Trust, London, UK., Marnat G; Department of Interventional and Diagnostic Neuroradiology, CHU Bordeaux, University of Bordeaux, Bordeaux, France., Sibon I; Stroke Unit, CHU Bordeaux, University of Bordeaux, Bordeaux, France., Nikoubashman O; Department of Neuroradiology, University Hospital RWTH Aachen, Aachen, Germany., Reich A; Department of Neurology, University Hospital RWTH Aachen, Aachen, Germany., Consoli A; Department of Stroke and Diagnostic and Interventional Neuroradiology, Foch Hospital, Suresnes, France., Lapergue B; Department of Stroke and Diagnostic and Interventional Neuroradiology, Foch Hospital, Suresnes, France., Ribo M; Stroke Unit, Department of Neurology, Hospital Vall d'Heborn, Barcelona, Spain., Tomasello A; Interventional Neuroradiology, Department of Radiology, Hospital Vall d'Heborn, Barcelona, Spain., Saleme S; Department of Neuroradiology, University Hospital of Limoges, Limoges, France., Macian F; Department of Neurology, University Hospital of Limoges, Limoges, France., Moulin S; Department of Neurology, CHU Reims, Reims, France., Pagano P; Department of Neuroradiology, CHU Reims, Reims, France., Saliou G; Service of Interventional and Diagnostic Radiology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland., Carrera E; Department of Neurology, Hôpitaux Universitaires de Genève, Geneva, Switzerland., Janot K; Department of Diagnostic and Interventional Neuroradiology, Tours University Hospital, Tours, France., Hernández-Pérez M; Stroke Unit, Department of Neurosciences, University Hospital Germans Trias i Pujol, Barcelona, Spain., Pop R; Department of Interventional Neuroradiology, Strasbourg University Hospitals, Strasbourg, France., Schiava LD; Department of Neurology, Lille University Hospital, Lille, France., Luft AR; Department of Neurology, University Hospital of Zurich, Zurich, Switzerland; Cereneo, Center for Neurology and Rehabilitation, Vitznau, Switzerland., Piotin M; Department of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France., Gentric JC; Department of Neuroradiology, Brest University Hospital, Brest, France; GETBO, INSERM Unit UMR 1034, Brest, France., Pikula A; Division of Neurology, Department of Medicine, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada., Pfeilschifter W; Department of Neurology, University Hospital Frankfurt, Frankfurt, Germany., Arnold M; Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Siddiqui AH; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, New York, NY, USA., Froehler MT; Vanderbilt Cerebrovascular Program, Vanderbilt University Medical Center, Nashville, TN, USA., Furlan AJ; School of Medicine, Case Western Reserve University, Cleveland, OH, USA., Chapot R; Department of Intracranial Endovascular Therapy, Alfried Krupp Krankenhaus Essen, Essen, Germany., Wiesmann M; Department of Neuroradiology, University Hospital RWTH Aachen, Aachen, Germany., Machi P; Department of Neuroradiology, Hôpitaux Universitaires de Genève, Geneva, Switzerland., Diener HC; Department of Neuroepidemiology, Institute for Medical Informatics, Biometry and Epidemiology IMIBE), Essen, Germany., Kulcsar Z; Department of Neuroradiology, University Hospital of Zurich, Zurich, Switzerland., Bonati LH; Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland., Bassetti CL; Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Mazighi M; Department of Neurology, Lariboisière Hospital, University of Paris, FHU NeuroVasc, INSERM 1148, Paris, France; Department of Interventional Neuroradiology, Adolphe de Rothschild Hospital Foundation, University of Paris, FHU NeuroVasc, INSERM 1148, Paris, France., Liebeskind DS; Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Saver JL; Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Gralla J; University Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. |
| Corporate Authors: | SWIFT DIRECT Collaborators |
| Source: | Lancet (London, England) [Lancet] 2022 Jul 09; Vol. 400 (10346), pp. 104-115. |
| Publication Type: | Equivalence Trial; Journal Article; Multicenter Study; Randomized Controlled Trial |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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