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Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities.

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Title: Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities.
Authors: Mallard TT; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Lead contact., Linnér RK; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Autism and Developmental Medicine Institute, Geisinger, Lewisburg, PA, USA., Grotzinger AD; Department of Psychology, University of Texas at Austin, Austin, TX, USA., Sanchez-Roige S; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Seidlitz J; Department of Child and Adolescent Psychiatry and Behavioral Science, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Okbay A; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., de Vlaming R; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Meddens SFW; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands., Palmer AA; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA., Davis LK; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Tucker-Drob EM; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA., Kendler KS; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Psychiatry, Medical College of Virginia/Virginia Commonwealth University, Richmond, VA, USA., Keller MC; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA., Koellinger PD; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Senior author., Harden KP; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA.; Senior author.
Corporate Authors: Bipolar Disorder Working Group of the Psychiatric Genomics Consortium
Source: Cell genomics [Cell Genom] 2022 Jun 08; Vol. 2 (6). Date of Electronic Publication: 2022 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities.
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  Data: <searchLink fieldCode="AU" term="%22Mallard+TT%22">Mallard TT</searchLink>; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Lead contact.<br /><searchLink fieldCode="AU" term="%22Linnér+RK%22">Linnér RK</searchLink>; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Autism and Developmental Medicine Institute, Geisinger, Lewisburg, PA, USA.<br /><searchLink fieldCode="AU" term="%22Grotzinger+AD%22">Grotzinger AD</searchLink>; Department of Psychology, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Sanchez-Roige+S%22">Sanchez-Roige S</searchLink>; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Seidlitz+J%22">Seidlitz J</searchLink>; Department of Child and Adolescent Psychiatry and Behavioral Science, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Okbay+A%22">Okbay A</searchLink>; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Vlaming+R%22">de Vlaming R</searchLink>; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Meddens+SFW%22">Meddens SFW</searchLink>; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Palmer+AA%22">Palmer AA</searchLink>; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Davis+LK%22">Davis LK</searchLink>; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Tucker-Drob+EM%22">Tucker-Drob EM</searchLink>; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kendler+KS%22">Kendler KS</searchLink>; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Psychiatry, Medical College of Virginia/Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Keller+MC%22">Keller MC</searchLink>; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Koellinger+PD%22">Koellinger PD</searchLink>; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Senior author.<br /><searchLink fieldCode="AU" term="%22Harden+KP%22">Harden KP</searchLink>; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA.; Senior author.
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  Data: <searchLink fieldCode="JN" term="%229918284260106676%22">Cell genomics</searchLink> [Cell Genom] 2022 Jun 08; Vol. 2 (6). <i>Date of Electronic Publication: </i>2022 Jun 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+Inc%22">Elsevier, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918284260106676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2666-979X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222666979X%22">2666979X </searchLink><i>NLM ISO Abbreviation: </i>Cell Genom <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.xgen.2022.100140
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        Text: English
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