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Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial.

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Title: Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial.
Authors: Oslin DW; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.; Department of Psychiatry, University of Pennsylvania, Philadelphia., Lynch KG; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.; Department of Psychiatry, University of Pennsylvania, Philadelphia., Shih MC; VA Cooperative Studies Coordinating Center, Palo Alto, California.; Department of Biomedical Data Science, Stanford University, Palo Alto, California., Ingram EP; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania., Wray LO; VA Center for Integrated Healthcare, Buffalo, New York.; VA Office of Mental Health and Suicide Prevention, Washington, DC.; Division of Geriatrics and Palliative Care, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York., Chapman SR; VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania., Kranzler HR; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.; Department of Psychiatry, University of Pennsylvania, Philadelphia., Gelernter J; VA Connecticut Healthcare System, West Haven.; Departments of Psychiatry, Genetics, and Neuroscience, Yale University School of Medicine, New Haven, Connecticut., Pyne JM; Central Arkansas Veterans Healthcare System, Little Rock.; Psychiatric Research Institute, University of Arkansas for Medical Sciences, Little Rock., Stone A; Central Arkansas Veterans Healthcare System, Little Rock., DuVall SL; VA Informatics and Computing Infrastructure, Salt Lake City, Utah.; VA Salt Lake City Health Care System, Salt Lake City, Utah.; Department of Internal Medicine Division of Epidemiology, University of Utah School of Medicine, Salt Lake City., Lehmann LS; VA Boston Healthcare System, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Google, Mountain View, California., Thase ME; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.; Department of Psychiatry, University of Pennsylvania, Philadelphia., Aslam M; Cincinnati VA Medical Center, Cincinnati, Ohio.; University of Cincinnati, Cincinnati, Ohio., Batki SL; San Francisco VA Health Care System, San Francisco, California.; Department of Psychiatry and Behavioral Sciences, UCSF Weill Institute for Neurosciences, San Francisco, California., Bjork JM; Hunter Holmes McGuire VA Medical Center, Richmond, Virginia.; Department of Psychiatry, Virginia Commonwealth University, Richmond., Blow FC; VA Center for Clinical Management Research, Ann Arbor, Michigan.; Department of Psychiatry, University of Michigan, Ann Arbor., Brenner LA; VA Rocky Mountain Mental Illness Research, Education, and Clinical Center, Rocky Mountain Regional VA Medical Center, Aurora, Colorado.; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology, University of Colorado Anschutz Medical Campus, Aurora., Chen P; Louis Stokes VA Medical Center, Cleveland, Ohio.; VISN 10 Geriatric Research, Education, and Clinical Center, Cleveland, Ohio.; Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, Ohio., Desai S; Hunter Holmes McGuire VA Medical Center, Richmond, Virginia., Dieperink EW; Minneapolis VA Health Care System, Minneapolis, Minnesota.; Department of Psychiatry, University of Minnesota Medical School, Minneapolis., Fears SC; VA Greater Los Angeles Healthcare System, Los Angeles, California.; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles., Fuller MA; Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, Ohio.; Veterans Health Administration Pharmacy Benefits Management Services, Washington, DC., Goodman CS; W.G. (Bill) Hefner VA Medical Center, Salisbury, North Carolina., Graham DP; Michael E. DeBakey VA Medical Center, Houston, Texas.; Menninger Department of Psychiatry, Baylor College of Medicine, Houston, Texas., Haas GL; VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania.; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Hamner MB; Ralph H. Johnson VA Medical Center, Charleston, South Carolina.; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston., Helstrom AW; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.; Department of Psychiatry, University of Pennsylvania, Philadelphia., Hurley RA; W.G. (Bill) Hefner VA Medical Center, Salisbury, North Carolina.; Departments of Psychiatry and Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina., Icardi MS; Iowa City VA Health Care System, Iowa City, Iowa.; Department of Pathology, University of Iowa, Iowa City., Jurjus GJ; Louis Stokes VA Medical Center, Cleveland, Ohio.; Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, Ohio., Kilbourne AM; VA Office of Research and Development, Washington, DC.; Department of Learning Health Sciences, University of Michigan Medical School, Ann Arbor., Kreyenbuhl J; VA Capitol Healthcare Network (VISN 5) Mental Illness Research, Education, and Clinical Center, Baltimore, Maryland.; Division of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore., Lache DJ; Wilmington VA Medical Center, Wilmington, Delaware.; Thomas Jefferson University, Philadelphia, Pennsylvania., Lieske SP; San Francisco VA Health Care System, San Francisco, California., Lynch JA; VA Salt Lake City Health Care System, Salt Lake City, Utah.; Department of Epidemiology, University of Utah School of Medicine, Salt Lake City., Meyer LJ; VA Salt Lake City Health Care System, Salt Lake City, Utah.; Departments of Dermatology and Internal Medicine, University of Utah, Salt Lake City., Montalvo C; VA Boston Healthcare System, Boston, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts., Muralidhar S; VA Office of Research and Development, Washington, DC.; VA Central Office, Washington, DC., Ostacher MJ; VA Palo Alto Health Care System, Palo Alto, California.; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California., Paschall GY; Central Arkansas Veterans Healthcare System, Little Rock., Pfeiffer PN; VA Center for Clinical Management Research, Ann Arbor, Michigan.; Department of Psychiatry, University of Michigan, Ann Arbor., Prieto S; Bruce W. Carter VA Medical Center, Miami, Florida., Przygodzki RM; VA Office of Research and Development, Washington, DC., Ranganathan M; VA Connecticut Healthcare System, West Haven.; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut., Rodriguez-Suarez MM; Bruce W. Carter VA Medical Center, Miami, Florida., Roggenkamp H; VA Greater Los Angeles Healthcare System, Los Angeles, California.; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles., Schichman SA; Central Arkansas Veterans Healthcare System, Little Rock.; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock., Schneeweis JS; US Army Veteran., Simonetti JA; VA Rocky Mountain Mental Illness Research, Education, and Clinical Center, Rocky Mountain Regional VA Medical Center, Aurora, Colorado.; Seattle-Denver Center of Innovation for Veteran-Centered and Value-Driven Care, Seattle, Washington, and Denver, Colorado.; Division of Hospital Medicine, University of Colorado Anschutz Medical Campus, Aurora., Steinhauer SR; VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania.; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Suppes T; VA Palo Alto Health Care System, Palo Alto, California.; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California., Umbert MA; Bruce W. Carter VA Medical Center, Miami, Florida., Vassy JL; VA Boston Healthcare System, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Voora D; Durham VA Medical Center, Durham, North Carolina.; Center for Applied Genomics & Precision Medicine, Duke University, Durham, North Carolina., Wiechers IR; VA Office of Mental Health and Suicide Prevention, Washington, DC.; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco., Wood AE; VA Puget Sound Health Care System, Tacoma, Washington.; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle.
Corporate Authors: PRIME Care Research Group
Source: JAMA [JAMA] 2022 Jul 12; Vol. 328 (2), pp. 151-161.
Publication Type: Comparative Study; Journal Article; Pragmatic Clinical Trial; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial.
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            NameFull: Przygodzki RM
      – PersonEntity:
          Name:
            NameFull: Ranganathan M
      – PersonEntity:
          Name:
            NameFull: Rodriguez-Suarez MM
      – PersonEntity:
          Name:
            NameFull: Roggenkamp H
      – PersonEntity:
          Name:
            NameFull: Schichman SA
      – PersonEntity:
          Name:
            NameFull: Schneeweis JS
      – PersonEntity:
          Name:
            NameFull: Simonetti JA
      – PersonEntity:
          Name:
            NameFull: Steinhauer SR
      – PersonEntity:
          Name:
            NameFull: Suppes T
      – PersonEntity:
          Name:
            NameFull: Umbert MA
      – PersonEntity:
          Name:
            NameFull: Vassy JL
      – PersonEntity:
          Name:
            NameFull: Voora D
      – PersonEntity:
          Name:
            NameFull: Wiechers IR
      – PersonEntity:
          Name:
            NameFull: Wood AE
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 12
              M: 07
              Text: 2022 Jul 12
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1538-3598
          Numbering:
            – Type: volume
              Value: 328
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: JAMA
              Type: main
ResultId 1