Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.

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Title: Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.
Authors: McCorvie TJ; Centre for Medicines Discovery, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Biosciences Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK., Loria PM; Discovery Sciences, Worldwide Research and Development, Pfizer Inc., Groton, CT, USA., Tu M; Medicine Design, Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Han S; Discovery Sciences, Worldwide Research and Development, Pfizer Inc., Groton, CT, USA., Shrestha L; Centre for Medicines Discovery, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Froese DS; Centre for Medicines Discovery, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.; Division of Metabolism and Children's Research Center, University Children's Hospital Zürich, University of Zürich, Zürich, Switzerland., Ferreira IM; Centre for Medicines Discovery, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Berg AP; Rare Disease Research Unit, Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA. allison.berg@pfizer.com., Yue WW; Centre for Medicines Discovery, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. wyatt.yue@cmd.ox.ac.uk.; Biosciences Institute, The Medical School, Newcastle University, Newcastle upon Tyne, UK. wyatt.yue@cmd.ox.ac.uk.
Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2022 Jul; Vol. 29 (7), pp. 628-638. Date of Electronic Publication: 2022 Jul 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1545-9985
DOI:10.1038/s41594-022-00799-3