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Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents: evidence for herd protection from the UK MenACWY programme.

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Title: Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents: evidence for herd protection from the UK MenACWY programme.
Authors: Carr JP; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK; Monash University and Monash Children's Hospital, Melbourne, Australia., MacLennan JM; Department of Biology, University of Oxford, Oxford, UK., Plested E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Bratcher HB; Department of Biology, University of Oxford, Oxford, UK., Harrison OB; Department of Biology, University of Oxford, Oxford, UK., Aley PK; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Bray JE; Department of Biology, University of Oxford, Oxford, UK., Camara S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Rodrigues CMC; Department of Biology, University of Oxford, Oxford, UK., Davis K; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Bartolf A; St George's Vaccine Institute, Institute of Infection & Immunity, St George's University of London, UK., Baxter D; Stockport NHS Foundation Trust, UK., Cameron JC; Public Health Scotland, Glasgow/Edinburgh, Scotland, UK., Cunningham R; University Hospitals Plymouth NHS Trust, Plymouth, UK., Faust SN; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK., Fidler K; Brighton and Sussex Medical School, Royal Alexandra Children's Hospital, University Hospital Sussex NHS Foundation Trust, Brighton, UK., Gowda R; Maidstone and Tunbridge Wells NHS Trust, UK., Heath PT; St George's Vaccine Institute, Institute of Infection & Immunity, St George's University of London, UK., Hughes S; Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, UK., Khajuria S; Northamptonshire Healthcare NHS Foundation Trust, UK., Orr D; Lancashire Teaching Hospitals NHS Foundation Trust, UK., Raman M; University Hospitals Plymouth NHS Foundation Trust, UK., Smith A; Glasgow Dental Hospital & School, College of Medical, Veterinary & Life Sciences, University of Glasgow, UK., Turner DPJ; School of Life Sciences, University of Nottingham & Nottingham University Hospitals NHS Trust, UK., Whittaker E; Paediatric Infectious Diseases, Imperial College Healthcare NHS Trust, London, UK; Section of Paediatric Infectious Diseases, Imperial College London, UK., Williams CJ; Communicable Disease Surveillance Centre, Public Health Wales, Cardiff, UK., Zipitis CS; Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust, UK., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK., Oliver J; Bristol Vaccine Centre, University of Bristol, UK; School of Population Health Sciences, Bristol Medical School, University of Bristol, UK., Morales-Aza B; Bristol Vaccine Centre, University of Bristol, UK., Lekshmi A; UK Health Security Agency Meningococcal Reference Unit, Manchester Royal Infirmary Manchester, UK., Clark SA; UK Health Security Agency Meningococcal Reference Unit, Manchester Royal Infirmary Manchester, UK., Borrow R; UK Health Security Agency Meningococcal Reference Unit, Manchester Royal Infirmary Manchester, UK., Christensen H; School of Population Health Sciences, Bristol Medical School, University of Bristol, UK., Trotter C; Department of Veterinary Medicine, University of Cambridge, UK., Finn A; Bristol Vaccine Centre, University of Bristol, UK; School of Population Health Sciences, Bristol Medical School, University of Bristol, UK., Maiden MC; Department of Biology, University of Oxford, Oxford, UK. Electronic address: martin.maiden@zoo.ox.ac.uk., Snape MD; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.
Corporate Authors: UKMenCar4 and ‘Be on the TEAM’ Study Collaborators
Source: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2022 Dec; Vol. 28 (12), pp. 1649.e1-1649.e8. Date of Electronic Publication: 2022 Jul 13.
Publication Type: Observational Study; Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9516420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0691 (Electronic) Linking ISSN: 1198743X NLM ISO Abbreviation: Clin Microbiol Infect Subsets: MEDLINE
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  Data: Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents: evidence for herd protection from the UK MenACWY programme.
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Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Bray+JE%22">Bray JE</searchLink>; Department of Biology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Camara+S%22">Camara S</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rodrigues+CMC%22">Rodrigues CMC</searchLink>; Department of Biology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Davis+K%22">Davis K</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Bartolf+A%22">Bartolf A</searchLink>; St George's Vaccine Institute, Institute of Infection & Immunity, St George's University of London, UK.<br /><searchLink fieldCode="AU" term="%22Baxter+D%22">Baxter D</searchLink>; Stockport NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Cameron+JC%22">Cameron JC</searchLink>; Public Health Scotland, Glasgow/Edinburgh, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Cunningham+R%22">Cunningham R</searchLink>; University Hospitals Plymouth NHS Trust, Plymouth, UK.<br /><searchLink fieldCode="AU" term="%22Faust+SN%22">Faust SN</searchLink>; NIHR Southampton Clinical Research Facility and NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Fidler+K%22">Fidler K</searchLink>; Brighton and Sussex Medical School, Royal Alexandra Children's Hospital, University Hospital Sussex NHS Foundation Trust, Brighton, UK.<br /><searchLink fieldCode="AU" term="%22Gowda+R%22">Gowda R</searchLink>; Maidstone and Tunbridge Wells NHS Trust, UK.<br /><searchLink fieldCode="AU" term="%22Heath+PT%22">Heath PT</searchLink>; St George's Vaccine Institute, Institute of Infection & Immunity, St George's University of London, UK.<br /><searchLink fieldCode="AU" term="%22Hughes+S%22">Hughes S</searchLink>; Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Khajuria+S%22">Khajuria S</searchLink>; Northamptonshire Healthcare NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Orr+D%22">Orr D</searchLink>; Lancashire Teaching Hospitals NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Raman+M%22">Raman M</searchLink>; University Hospitals Plymouth NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Smith+A%22">Smith A</searchLink>; Glasgow Dental Hospital & School, College of Medical, Veterinary & Life Sciences, University of Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Turner+DPJ%22">Turner DPJ</searchLink>; School of Life Sciences, University of Nottingham & Nottingham University Hospitals NHS Trust, UK.<br /><searchLink fieldCode="AU" term="%22Whittaker+E%22">Whittaker E</searchLink>; Paediatric Infectious Diseases, Imperial College Healthcare NHS Trust, London, UK; Section of Paediatric Infectious Diseases, Imperial College London, UK.<br /><searchLink fieldCode="AU" term="%22Williams+CJ%22">Williams CJ</searchLink>; Communicable Disease Surveillance Centre, Public Health Wales, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Zipitis+CS%22">Zipitis CS</searchLink>; Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust, UK.<br /><searchLink fieldCode="AU" term="%22Pollard+AJ%22">Pollard AJ</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Oliver+J%22">Oliver J</searchLink>; Bristol Vaccine Centre, University of Bristol, UK; School of Population Health Sciences, Bristol Medical School, University of Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Morales-Aza+B%22">Morales-Aza B</searchLink>; Bristol Vaccine Centre, University of Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Lekshmi+A%22">Lekshmi A</searchLink>; UK Health Security Agency Meningococcal Reference Unit, Manchester Royal Infirmary Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Clark+SA%22">Clark SA</searchLink>; UK Health Security Agency Meningococcal Reference Unit, Manchester Royal Infirmary Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Borrow+R%22">Borrow R</searchLink>; UK Health Security Agency Meningococcal Reference Unit, Manchester Royal Infirmary Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Christensen+H%22">Christensen H</searchLink>; School of Population Health Sciences, Bristol Medical School, University of Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Trotter+C%22">Trotter C</searchLink>; Department of Veterinary Medicine, University of Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Finn+A%22">Finn A</searchLink>; Bristol Vaccine Centre, University of Bristol, UK; School of Population Health Sciences, Bristol Medical School, University of Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Maiden+MC%22">Maiden MC</searchLink>; Department of Biology, University of Oxford, Oxford, UK. Electronic address: martin.maiden@zoo.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Snape+MD%22">Snape MD</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.
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