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Reactive astrogliosis is associated with higher cerebral glucose consumption in the early Alzheimer's continuum.

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Title: Reactive astrogliosis is associated with higher cerebral glucose consumption in the early Alzheimer's continuum.
Authors: Salvadó G; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain., Milà-Alomà M; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Shekari M; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.; Institute of Psychiatry, King's College London, Maurice Wohl Clinical Neuroscience Institute, Psychology & Neuroscience, London, UK.; NIHR Biomedical Research Centre for Mental Health & Biomedical Research Unit for Dementia at South London & Maudsley NHS Foundation, London, UK., Operto G; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain., Falcon C; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red Bioingeniería, (CIBER-BBN), Biomateriales Y Nanomedicina, Barcelona, Spain., Cacciaglia R; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain., Minguillon C; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain., Fauria K; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain., Niñerola-Baizán A; Centro de Investigación Biomédica en Red Bioingeniería, (CIBER-BBN), Biomateriales Y Nanomedicina, Barcelona, Spain.; Nuclear Medicine Department, Hospital Clínic Barcelona, Barcelona, Spain., Perissinotti A; Centro de Investigación Biomédica en Red Bioingeniería, (CIBER-BBN), Biomateriales Y Nanomedicina, Barcelona, Spain.; Nuclear Medicine Department, Hospital Clínic Barcelona, Barcelona, Spain., Benedet AL; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, McGill University, Montreal, QC, Canada., Kollmorgen G; Roche Diagnostics GmbH, Penzberg, Germany., Suridjan I; Roche Diagnostics International Ltd, Rotkreuz, Switzerland., Wild N; Roche Diagnostics GmbH, Penzberg, Germany., Molinuevo JL; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; H. Lundbeck A/S, Copenhagen, Denmark., Zetterberg H; Universitat Pompeu Fabra, Barcelona, Spain.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China., Blennow K; Universitat Pompeu Fabra, Barcelona, Spain.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Suárez-Calvet M; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain. msuarez@barcelonabeta.org.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. msuarez@barcelonabeta.org.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain. msuarez@barcelonabeta.org.; Servei de Neurologia, Hospital del Mar, Barcelona, Spain. msuarez@barcelonabeta.org., Gispert JD; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain. jdgispert@barcelonabeta.org.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. jdgispert@barcelonabeta.org.; Centro de Investigación Biomédica en Red Bioingeniería, (CIBER-BBN), Biomateriales Y Nanomedicina, Barcelona, Spain. jdgispert@barcelonabeta.org.
Corporate Authors: ALFA Study
Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2022 Nov; Vol. 49 (13), pp. 4567-4579. Date of Electronic Publication: 2022 Jul 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Reactive astrogliosis is associated with higher cerebral glucose consumption in the early Alzheimer's continuum.
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  Data: <searchLink fieldCode="AU" term="%22Salvadó+G%22">Salvadó G</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Milà-Alomà+M%22">Milà-Alomà M</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Shekari+M%22">Shekari M</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ashton+NJ%22">Ashton NJ</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.; Institute of Psychiatry, King's College London, Maurice Wohl Clinical Neuroscience Institute, Psychology & Neuroscience, London, UK.; NIHR Biomedical Research Centre for Mental Health & Biomedical Research Unit for Dementia at South London & Maudsley NHS Foundation, London, UK.<br /><searchLink fieldCode="AU" term="%22Operto+G%22">Operto G</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Falcon+C%22">Falcon C</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red Bioingeniería, (CIBER-BBN), Biomateriales Y Nanomedicina, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cacciaglia+R%22">Cacciaglia R</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Minguillon+C%22">Minguillon C</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Fauria+K%22">Fauria K</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Niñerola-Baizán+A%22">Niñerola-Baizán A</searchLink>; Centro de Investigación Biomédica en Red Bioingeniería, (CIBER-BBN), Biomateriales Y Nanomedicina, Barcelona, Spain.; Nuclear Medicine Department, Hospital Clínic Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Perissinotti+A%22">Perissinotti A</searchLink>; Centro de Investigación Biomédica en Red Bioingeniería, (CIBER-BBN), Biomateriales Y Nanomedicina, Barcelona, Spain.; Nuclear Medicine Department, Hospital Clínic Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Benedet+AL%22">Benedet AL</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Kollmorgen+G%22">Kollmorgen G</searchLink>; Roche Diagnostics GmbH, Penzberg, Germany.<br /><searchLink fieldCode="AU" term="%22Suridjan+I%22">Suridjan I</searchLink>; Roche Diagnostics International Ltd, Rotkreuz, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wild+N%22">Wild N</searchLink>; Roche Diagnostics GmbH, Penzberg, Germany.<br /><searchLink fieldCode="AU" term="%22Molinuevo+JL%22">Molinuevo JL</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain.; H. Lundbeck A/S, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Universitat Pompeu Fabra, Barcelona, Spain.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Universitat Pompeu Fabra, Barcelona, Spain.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Suárez-Calvet+M%22">Suárez-Calvet M</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain. msuarez@barcelonabeta.org.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. msuarez@barcelonabeta.org.; Centro de Investigación Biomédica en Red de Fragilidad Y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain. msuarez@barcelonabeta.org.; Servei de Neurologia, Hospital del Mar, Barcelona, Spain. msuarez@barcelonabeta.org.<br /><searchLink fieldCode="AU" term="%22Gispert+JD%22">Gispert JD</searchLink>; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, C/ Wellington, 30, 08005, Barcelona, Spain. jdgispert@barcelonabeta.org.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. jdgispert@barcelonabeta.org.; Centro de Investigación Biomédica en Red Bioingeniería, (CIBER-BBN), Biomateriales Y Nanomedicina, Barcelona, Spain. jdgispert@barcelonabeta.org.
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