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Activation of CD44/PAK1/AKT signaling promotes resistance to FGFR1 inhibition in squamous-cell lung cancer.

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Title: Activation of CD44/PAK1/AKT signaling promotes resistance to FGFR1 inhibition in squamous-cell lung cancer.
Authors: Elakad O; Institute of Pathology, University Medical Center, Goettingen, Germany., Häupl B; Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt, Germany.; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt, Germany., Labitzky V; Institute for Anatomy and Experimental Morphology, University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Yao S; Institute of Pathology, University Medical Center, Goettingen, Germany., Küffer S; Institute of Pathology, University Medical Center, Goettingen, Germany., von Hammerstein-Equord A; Department of Thoracic and Cardiovascular Surgery, University Medical Center, Goettingen, Germany., Danner BC; Department of Thoracic and Cardiovascular Surgery, University Medical Center, Goettingen, Germany., Jücker M; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Urlaub H; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany., Lange T; Institute for Anatomy and Experimental Morphology, University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ströbel P; Institute of Pathology, University Medical Center, Goettingen, Germany., Oellerich T; Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt, Germany.; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt, Germany., Bohnenberger H; Institute of Pathology, University Medical Center, Goettingen, Germany. Hanibal.bohnenberger@med.uni-goettingen.de.
Source: NPJ precision oncology [NPJ Precis Oncol] 2022 Jul 19; Vol. 6 (1), pp. 52. Date of Electronic Publication: 2022 Jul 19.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Activation of CD44/PAK1/AKT signaling promotes resistance to FGFR1 inhibition in squamous-cell lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Elakad+O%22">Elakad O</searchLink>; Institute of Pathology, University Medical Center, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Häupl+B%22">Häupl B</searchLink>; Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt, Germany.; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Labitzky+V%22">Labitzky V</searchLink>; Institute for Anatomy and Experimental Morphology, University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Yao+S%22">Yao S</searchLink>; Institute of Pathology, University Medical Center, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Küffer+S%22">Küffer S</searchLink>; Institute of Pathology, University Medical Center, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22von+Hammerstein-Equord+A%22">von Hammerstein-Equord A</searchLink>; Department of Thoracic and Cardiovascular Surgery, University Medical Center, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Danner+BC%22">Danner BC</searchLink>; Department of Thoracic and Cardiovascular Surgery, University Medical Center, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Jücker+M%22">Jücker M</searchLink>; Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Urlaub+H%22">Urlaub H</searchLink>; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Lange+T%22">Lange T</searchLink>; Institute for Anatomy and Experimental Morphology, University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ströbel+P%22">Ströbel P</searchLink>; Institute of Pathology, University Medical Center, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Oellerich+T%22">Oellerich T</searchLink>; Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt, Germany.; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Bohnenberger+H%22">Bohnenberger H</searchLink>; Institute of Pathology, University Medical Center, Goettingen, Germany. Hanibal.bohnenberger@med.uni-goettingen.de.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
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