ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
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| Title: | ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. |
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| Authors: | Low JS; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.; Institute of Microbiology, ETH Zürich, 8093 Zurich, Switzerland., Jerak J; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.; Institute of Microbiology, ETH Zürich, 8093 Zurich, Switzerland., Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., McCallum M; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Pinto D; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland., Cassotta A; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland., Foglierini M; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland., Mele F; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland., Abdelnabi R; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium., Weynand B; KU Leuven Department of Imaging and Pathology, Translational Cell and Tissue Research, B-3000 Leuven, Belgium., Noack J; Vir Biotechnology, San Francisco, CA 94158, USA., Montiel-Ruiz M; Vir Biotechnology, San Francisco, CA 94158, USA., Bianchi S; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland., Benigni F; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland., Sprugasci N; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland., Joshi A; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Stewart C; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Rexhepaj M; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Howard Hughes Medical Institute, Seattle, WA 98195, USA., Jarrossay D; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland., Morone D; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland., Paparoditis P; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland., Garzoni C; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland., Ferrari P; Faculty of Biomedical Sciences, Università della Svizzera Italiana, 6900 Lugano, Switzerland.; Department of Internal Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Prince of Wales Hospital Clinical School, University of New South Wales, Sydney, New South Wales 2052, Australia., Ceschi A; Faculty of Biomedical Sciences, Università della Svizzera Italiana, 6900 Lugano, Switzerland.; Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.; Clinical Trial Unit, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, 8091 Zurich, Switzerland., Neyts J; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.; Global Virus Network, Baltimore, MD 21201, USA., Purcell LA; Vir Biotechnology, San Francisco, CA 94158, USA., Snell G; Vir Biotechnology, San Francisco, CA 94158, USA., Corti D; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland., Lanzavecchia A; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland.; National Institute of Molecular Genetics, 20122 Milano, Italy., Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Howard Hughes Medical Institute, Seattle, WA 98195, USA., Sallusto F; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.; Institute of Microbiology, ETH Zürich, 8093 Zurich, Switzerland. |
| Source: | Science (New York, N.Y.) [Science] 2022 Aug 12; Vol. 377 (6607), pp. 735-742. Date of Electronic Publication: 2022 Jul 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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