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Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures.

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Title: Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures.
Authors: Roden CA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Dai Y; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA., Giannetti CA; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Seim I; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Lee M; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520, USA., Sealfon R; Flatiron Institute, Simons Foundation, New York, NY 10010, USA., McLaughlin GA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Boerneke MA; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Iserman C; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Wey SA; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Ekena JL; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Troyanskaya OG; Flatiron Institute, Simons Foundation, New York, NY 10010, USA.; Department of Computer Science, Princeton University, Princeton, NJ 08540, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA., Weeks KM; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., You L; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27708, USA., Chilkoti A; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA., Gladfelter AS; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Source: Nucleic acids research [Nucleic Acids Res] 2022 Aug 12; Vol. 50 (14), pp. 8168-8192.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures.
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  Data: <searchLink fieldCode="AU" term="%22Roden+CA%22">Roden CA</searchLink>; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.<br /><searchLink fieldCode="AU" term="%22Dai+Y%22">Dai Y</searchLink>; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.<br /><searchLink fieldCode="AU" term="%22Giannetti+CA%22">Giannetti CA</searchLink>; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.<br /><searchLink fieldCode="AU" term="%22Seim+I%22">Seim I</searchLink>; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520, USA.<br /><searchLink fieldCode="AU" term="%22Sealfon+R%22">Sealfon R</searchLink>; Flatiron Institute, Simons Foundation, New York, NY 10010, USA.<br /><searchLink fieldCode="AU" term="%22McLaughlin+GA%22">McLaughlin GA</searchLink>; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Boerneke+MA%22">Boerneke MA</searchLink>; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.<br /><searchLink fieldCode="AU" term="%22Iserman+C%22">Iserman C</searchLink>; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Wey+SA%22">Wey SA</searchLink>; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.<br /><searchLink fieldCode="AU" term="%22Ekena+JL%22">Ekena JL</searchLink>; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Troyanskaya+OG%22">Troyanskaya OG</searchLink>; Flatiron Institute, Simons Foundation, New York, NY 10010, USA.; Department of Computer Science, Princeton University, Princeton, NJ 08540, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA.<br /><searchLink fieldCode="AU" term="%22Weeks+KM%22">Weeks KM</searchLink>; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.<br /><searchLink fieldCode="AU" term="%22You+L%22">You L</searchLink>; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27708, USA.<br /><searchLink fieldCode="AU" term="%22Chilkoti+A%22">Chilkoti A</searchLink>; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.<br /><searchLink fieldCode="AU" term="%22Gladfelter+AS%22">Gladfelter AS</searchLink>; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
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