Population-based plasma lipidomics reveals developmental changes in metabolism and signatures of obesity risk: a mother-offspring cohort study.
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| Title: | Population-based plasma lipidomics reveals developmental changes in metabolism and signatures of obesity risk: a mother-offspring cohort study. |
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| Authors: | Mir SA; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore.; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Chen L; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore., Burugupalli S; Metabolomics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia., Burla B; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Ji S; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Smith AAT; Metabolomics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia., Narasimhan K; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore., Ramasamy A; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore., Tan KM; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore., Huynh K; Metabolomics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia., Giles C; Metabolomics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia., Mei D; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Wong G; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore., Yap F; KK Women's and Children's Hospital, Singapore, Singapore., Tan KH; KK Women's and Children's Hospital, Singapore, Singapore., Collier F; School of Medicine, Deakin University, Geelong, Australia.; Child Health Research Unit, Barwon Health, Geelong, Australia.; Murdoch Children's Research Institute, University of Melbourne, Parkville, Australia., Saffery R; Murdoch Children's Research Institute, University of Melbourne, Parkville, Australia.; The Florey Institute of Neuroscience and Mental Health, Parkville, Australia., Vuillermin P; School of Medicine, Deakin University, Geelong, Australia.; Child Health Research Unit, Barwon Health, Geelong, Australia.; Murdoch Children's Research Institute, University of Melbourne, Parkville, Australia., Bendt AK; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Burgner D; Murdoch Children's Research Institute, University of Melbourne, Parkville, Australia.; The Florey Institute of Neuroscience and Mental Health, Parkville, Australia., Ponsonby AL; Murdoch Children's Research Institute, University of Melbourne, Parkville, Australia.; The Florey Institute of Neuroscience and Mental Health, Parkville, Australia., Lee YS; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore.; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chong YS; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Gluckman PD; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore.; Centre for Human Evolution, Adaptation and Disease, Liggins Institute, University of Auckland, Auckland, New Zealand., Eriksson JG; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore.; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Folkhalsan Research Center, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland., Meikle PJ; Metabolomics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia. Peter.Meikle@baker.edu.au., Wenk MR; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore. bchmrw@nus.edu.sg.; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, Singapore. bchmrw@nus.edu.sg., Karnani N; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore. neerja_karnani@sics.a-star.edu.sg.; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Brenner Centre for Molecular Medicine, 30 Medical Drive, Singapore, 117609, Singapore. neerja_karnani@sics.a-star.edu.sg.; DataHub Division, Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore. neerja_karnani@sics.a-star.edu.sg. |
| Source: | BMC medicine [BMC Med] 2022 Jul 25; Vol. 20 (1), pp. 242. Date of Electronic Publication: 2022 Jul 25. |
| Publication Type: | Journal Article; Observational Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1741-7015 |
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| DOI: | 10.1186/s12916-022-02432-y |
