Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.
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| Title: | Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC. |
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| Authors: | Saddawi-Konefka R; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA. rsaddawi@health.ucsd.edu.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA. rsaddawi@health.ucsd.edu.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA. rsaddawi@health.ucsd.edu., O'Farrell A; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Faraji F; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA., Clubb L; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Allevato MM; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Jensen SM; Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR, USA., Yung BS; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Wang Z; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Wu VH; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Anang NA; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Msari RA; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Schokrpur S; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, Division of Hematology-Oncology, UC San Diego School of Medicine, San Diego, CA, USA., Pietryga IF; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Molinolo AA; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Mesirov JP; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, UC San Diego School of Medicine, La Jolla, CA, USA., Simon AB; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Radiation Oncology, UC Irvine School of Medicine, Irvine, CA, USA., Fox BA; Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR, USA.; Department of Molecular Microbiology and Immunology, Oregon Health Science University, Portland, OR, USA., Bui JD; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Pathology, UC San Diego School of Medicine, La Jolla, CA, USA., Sharabi A; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Radiation Medicine and Applied Sciences, UC San Diego School of Medicine, San Diego, CA, USA., Cohen EEW; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, Division of Hematology-Oncology, UC San Diego School of Medicine, San Diego, CA, USA., Califano JA; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA., Gutkind JS; Moores Cancer Center, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu.; Department of Pharmacology, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu. |
| Source: | Nature communications [Nat Commun] 2022 Jul 25; Vol. 13 (1), pp. 4298. Date of Electronic Publication: 2022 Jul 25. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-022-31941-w |
