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Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.

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Title: Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.
Authors: Saddawi-Konefka R; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA. rsaddawi@health.ucsd.edu.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA. rsaddawi@health.ucsd.edu.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA. rsaddawi@health.ucsd.edu., O'Farrell A; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Faraji F; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA., Clubb L; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Allevato MM; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Jensen SM; Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR, USA., Yung BS; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Wang Z; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Wu VH; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Anang NA; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Msari RA; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Schokrpur S; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, Division of Hematology-Oncology, UC San Diego School of Medicine, San Diego, CA, USA., Pietryga IF; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Molinolo AA; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Mesirov JP; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, UC San Diego School of Medicine, La Jolla, CA, USA., Simon AB; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Radiation Oncology, UC Irvine School of Medicine, Irvine, CA, USA., Fox BA; Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR, USA.; Department of Molecular Microbiology and Immunology, Oregon Health Science University, Portland, OR, USA., Bui JD; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Pathology, UC San Diego School of Medicine, La Jolla, CA, USA., Sharabi A; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Radiation Medicine and Applied Sciences, UC San Diego School of Medicine, San Diego, CA, USA., Cohen EEW; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, Division of Hematology-Oncology, UC San Diego School of Medicine, San Diego, CA, USA., Califano JA; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA., Gutkind JS; Moores Cancer Center, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu.; Department of Pharmacology, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu.
Source: Nature communications [Nat Commun] 2022 Jul 25; Vol. 13 (1), pp. 4298. Date of Electronic Publication: 2022 Jul 25.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.
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  Data: <searchLink fieldCode="AU" term="%22Saddawi-Konefka+R%22">Saddawi-Konefka R</searchLink>; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA. rsaddawi@health.ucsd.edu.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA. rsaddawi@health.ucsd.edu.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA. rsaddawi@health.ucsd.edu.<br /><searchLink fieldCode="AU" term="%22O'Farrell+A%22">O'Farrell A</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Faraji+F%22">Faraji F</searchLink>; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Clubb+L%22">Clubb L</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Allevato+MM%22">Allevato MM</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jensen+SM%22">Jensen SM</searchLink>; Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Yung+BS%22">Yung BS</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+VH%22">Wu VH</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Anang+NA%22">Anang NA</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Msari+RA%22">Msari RA</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schokrpur+S%22">Schokrpur S</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, Division of Hematology-Oncology, UC San Diego School of Medicine, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pietryga+IF%22">Pietryga IF</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Molinolo+AA%22">Molinolo AA</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mesirov+JP%22">Mesirov JP</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, UC San Diego School of Medicine, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Simon+AB%22">Simon AB</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Radiation Oncology, UC Irvine School of Medicine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fox+BA%22">Fox BA</searchLink>; Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR, USA.; Department of Molecular Microbiology and Immunology, Oregon Health Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Bui+JD%22">Bui JD</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Pathology, UC San Diego School of Medicine, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sharabi+A%22">Sharabi A</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Radiation Medicine and Applied Sciences, UC San Diego School of Medicine, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+EEW%22">Cohen EEW</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.; Department of Medicine, Division of Hematology-Oncology, UC San Diego School of Medicine, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Califano+JA%22">Califano JA</searchLink>; Department of Otolaryngology-Head and Neck Surgery, UC San Diego School of Medicine, San Diego, CA, USA.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gutkind+JS%22">Gutkind JS</searchLink>; Moores Cancer Center, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu.; Gleiberman Head and Neck Cancer Center, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu.; Department of Pharmacology, UC San Diego, La Jolla, CA, USA. sgutkind@health.ucsd.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Jul 25; Vol. 13 (1), pp. 4298. <i>Date of Electronic Publication: </i>2022 Jul 25.
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