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CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-β signaling.

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Title: CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-β signaling.
Authors: Fix SM; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Forget MA; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Sakellariou-Thompson D; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Wang Y; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Griffiths TM; Biologics Development, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Lee M; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Haymaker CL; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Dominguez AL; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Basar R; Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Reyes C; Cell Biology R&D, Thermo Fisher Scientific, Carlsbad, California, USA., Kumar S; Cell Biology R&D, Thermo Fisher Scientific, Carlsbad, California, USA., Meyer LA; Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Hwu P; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Patrick.Hwu@moffitt.org., Bernatchez C; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Jazaeri AA; Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2022 Jul; Vol. 10 (7).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-β signaling.
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  Data: <searchLink fieldCode="AU" term="%22Fix+SM%22">Fix SM</searchLink>; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Forget+MA%22">Forget MA</searchLink>; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Sakellariou-Thompson+D%22">Sakellariou-Thompson D</searchLink>; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Griffiths+TM%22">Griffiths TM</searchLink>; Biologics Development, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Haymaker+CL%22">Haymaker CL</searchLink>; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Dominguez+AL%22">Dominguez AL</searchLink>; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Basar+R%22">Basar R</searchLink>; Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Reyes+C%22">Reyes C</searchLink>; Cell Biology R&D, Thermo Fisher Scientific, Carlsbad, California, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+S%22">Kumar S</searchLink>; Cell Biology R&D, Thermo Fisher Scientific, Carlsbad, California, USA.<br /><searchLink fieldCode="AU" term="%22Meyer+LA%22">Meyer LA</searchLink>; Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Hwu+P%22">Hwu P</searchLink>; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Patrick.Hwu@moffitt.org.<br /><searchLink fieldCode="AU" term="%22Bernatchez+C%22">Bernatchez C</searchLink>; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Jazaeri+AA%22">Jazaeri AA</searchLink>; Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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  Data: <searchLink fieldCode="JN" term="%22101620585%22">Journal for immunotherapy of cancer</searchLink> [J Immunother Cancer] 2022 Jul; Vol. 10 (7).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ+Publishing+Group+Ltd%22">BMJ Publishing Group Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101620585 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-1426 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220511426%22">20511426 </searchLink><i>NLM ISO Abbreviation: </i>J Immunother Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1136/jitc-2021-003750
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        Text: English
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              M: 07
              Text: 2022 Jul
              Type: published
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