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Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis.

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Title: Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis.
Authors: Cavalcanti F; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Gonzalez-Rey E; Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, PTS-Granada, 18016 Granada, Spain., Delgado M; Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, PTS-Granada, 18016 Granada, Spain., Falo CP; Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, PTS-Granada, 18016 Granada, Spain., Mestre L; Department of Functional and Systems Neurobiology, Cajal Institute (CSIC), 28034 Madrid, Spain., Guaza C; Department of Functional and Systems Neurobiology, Cajal Institute (CSIC), 28034 Madrid, Spain., O'Valle F; Department of Pathology, School of Medicine, IBIMER and IBS-Granada, Granada University, 18071 Granada, Spain., Lufino MMP; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Xaus J; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Mascaró C; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Lunardi S; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Sacilotto N; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Dessanti P; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Rotllant D; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Navarro X; Departament de Biologia Cellular, Fisiologia i Immunologia, Institut de Neurociències, Universitat Autònoma de Barcelona, and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08193 Barcelona, Spain., Herrando-Grabulosa M; Departament de Biologia Cellular, Fisiologia i Immunologia, Institut de Neurociències, Universitat Autònoma de Barcelona, and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08193 Barcelona, Spain., Buesa C; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain., Maes T; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.
Source: Pharmaceutics [Pharmaceutics] 2022 Jul 06; Vol. 14 (7). Date of Electronic Publication: 2022 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Cavalcanti+F%22">Cavalcanti F</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Rey+E%22">Gonzalez-Rey E</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, PTS-Granada, 18016 Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Delgado+M%22">Delgado M</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, PTS-Granada, 18016 Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Falo+CP%22">Falo CP</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, PTS-Granada, 18016 Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Mestre+L%22">Mestre L</searchLink>; Department of Functional and Systems Neurobiology, Cajal Institute (CSIC), 28034 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Guaza+C%22">Guaza C</searchLink>; Department of Functional and Systems Neurobiology, Cajal Institute (CSIC), 28034 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22O'Valle+F%22">O'Valle F</searchLink>; Department of Pathology, School of Medicine, IBIMER and IBS-Granada, Granada University, 18071 Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Lufino+MMP%22">Lufino MMP</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Xaus+J%22">Xaus J</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Mascaró+C%22">Mascaró C</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Lunardi+S%22">Lunardi S</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Sacilotto+N%22">Sacilotto N</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Dessanti+P%22">Dessanti P</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Rotllant+D%22">Rotllant D</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Navarro+X%22">Navarro X</searchLink>; Departament de Biologia Cellular, Fisiologia i Immunologia, Institut de Neurociències, Universitat Autònoma de Barcelona, and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08193 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Herrando-Grabulosa+M%22">Herrando-Grabulosa M</searchLink>; Departament de Biologia Cellular, Fisiologia i Immunologia, Institut de Neurociències, Universitat Autònoma de Barcelona, and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 08193 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Buesa+C%22">Buesa C</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.<br /><searchLink fieldCode="AU" term="%22Maes+T%22">Maes T</searchLink>; Oryzon Genomics S.A., Carrer Sant Ferran 74, 08940 Cornellà de Llobregat, Spain.
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              Text: 2022 Jul 06
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