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Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA.

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Title: Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA.
Authors: Sánchez R; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain. ricardsanchez.hdoc@gmail.com.; Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain. ricardsanchez.hdoc@gmail.com.; Hematological Malignancies Clinical Research Unit, CNIO, Madrid, Spain. ricardsanchez.hdoc@gmail.com.; Altum Sequencing Co., Madrid, Spain. ricardsanchez.hdoc@gmail.com., Dorado S; Altum Sequencing Co., Madrid, Spain.; Computer Science and Engineering Department, Carlos III University, Madrid, Spain., Ruíz-Heredia Y; Altum Sequencing Co., Madrid, Spain., Martín-Muñoz A; Altum Sequencing Co., Madrid, Spain., Rosa-Rosa JM; Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain.; Hematological Malignancies Clinical Research Unit, CNIO, Madrid, Spain., Ribera J; Hematology Department, ICO-Hospital Germans Trias i Pujol. Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain., García O; Hematology Department, ICO-Hospital Germans Trias i Pujol. Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain., Jimenez-Ubieto A; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain.; Hematological Malignancies Clinical Research Unit, CNIO, Madrid, Spain., Carreño-Tarragona G; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain.; Hematological Malignancies Clinical Research Unit, CNIO, Madrid, Spain., Linares M; Hematological Malignancies Clinical Research Unit, CNIO, Madrid, Spain.; Department of Biochemistry and Molecular Biology, Pharmacy School, Universidad Complutense de Madrid, Madrid, Spain., Rufián L; Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain.; Altum Sequencing Co., Madrid, Spain., Juárez A; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain.; Altum Sequencing Co., Madrid, Spain., Carrillo J; Altum Sequencing Co., Madrid, Spain., Espino MJ; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain., Cáceres M; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain., Expósito S; Laboratory of Neurophysiology and Synaptic Plasticity, Instituto Cajal, CSIC, Madrid, Spain., Cuevas B; Hospital Universitario de Burgos, Burgos, Spain., Vanegas R; Hospital General Universitario de Ciudad Real, Ciudad Real, Spain., Casado LF; Hospital Virgen de la Salud, Toledo, Spain., Torrent A; Hematology Department, ICO-Hospital Germans Trias i Pujol. Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain., Zamora L; Hematology Department, ICO-Hospital Germans Trias i Pujol. Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain., Mercadal S; Hematology Department, ICO-Hospital Duran i Reynals (Bellvitge), Barcelona, Spain., Coll R; Hematology Department, ICO-Hospital Dr. Josep Trueta, Girona, Spain., Cervera M; Hematology Department, ICO-Hospital Universitari Joan XXIII, Tarragona, Spain., Morgades M; Hematology Department, ICO-Hospital Germans Trias i Pujol. Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain., Hernández-Rivas JÁ; Hospital Universitario Infanta Leonor, Madrid, Spain., Bravo P; Hospital Universitario de Fuenlabrada, Fuenlabrada (Madrid), Spain., Serí C; Hospital Central de la Defensa Gómez Ulla, Madrid, Spain., Anguita E; Hospital Clínico San Carlos, Department of Medicine, UCM, Madrid, Spain., Barragán E; Hospital Universitario y Politécnico La Fe, Valencia, Spain., Sargas C; Hospital Universitario y Politécnico La Fe, Valencia, Spain., Ferrer-Marín F; Hospital Universitario Morales-Meseguer, IMIB-Arrixaca, CIBERER, UCAM, Murcia, Spain., Sánchez-Calero J; Hospital Universitario de Móstoles, Móstoles (Madrid), Spain., Sevilla J; Hospital Universitario Niño Jesús, Madrid, Spain., Ruíz E; Hospital del Tajo, Aranjuez (Madrid), Spain., Villalón L; Hospital Universitario Fundación Alcorcón, Alcorcón (Madrid), Spain., Del Mar Herráez M; Hospital Santa Bárbara, Puertollano, Ciudad Real, Spain., Riaza R; Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain., Magro E; Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain., Steegman JL; Hospital Universitario La Princesa, Madrid, Spain., Wang C; Hosea Precision Medical Technology Co., Ltd., Weihai, Shangdong, China., de Toledo P; Computer Science and Engineering Department, Carlos III University, Madrid, Spain., García-Gutiérrez V; Hospital Universitario Ramón y Cajal, Instituto de Investigación IRYCIS, Madrid, Spain., Ayala R; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain.; Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain.; Hematological Malignancies Clinical Research Unit, CNIO, Madrid, Spain.; Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain., Ribera JM; Hematology Department, ICO-Hospital Germans Trias i Pujol. Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain., Barrio S; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain.; Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain.; Hematological Malignancies Clinical Research Unit, CNIO, Madrid, Spain.; Altum Sequencing Co., Madrid, Spain., Martínez-López J; Hematology Department, Hospital UniversitarioHospital Universitario 12 Octubre, Madrid, Spain. jmarti01@med.ucm.es.; Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain. jmarti01@med.ucm.es.; Hematological Malignancies Clinical Research Unit, CNIO, Madrid, Spain. jmarti01@med.ucm.es.; Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain. jmarti01@med.ucm.es.
Source: Scientific reports [Sci Rep] 2022 Jul 29; Vol. 12 (1), pp. 13057. Date of Electronic Publication: 2022 Jul 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-022-17271-3