Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinoma.

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Title: Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinoma.
Authors: Hinshaw DC; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Swain CA; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Chen D; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.; Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.; Center for Clinical and Translational Sciences, University of Alabama at Birmingham, Birmingham, AL, USA., Hanna A; Vanderbilt Center for Immunobiology, Vanderbilt University School of Medicine, Nashville, TN, USA., Molina PA; Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Maynard CL; Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Lee G; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., McFarland BC; Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Samant RS; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.; Birmingham VA Medical Center, Birmingham, AL, USA., Shevde LA; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA. lsamant@uab.edu.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA. lsamant@uab.edu.
Source: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2022 Nov; Vol. 102 (11), pp. 1236-1244. Date of Electronic Publication: 2022 Jul 30.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0376617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0307 (Electronic) Linking ISSN: 00236837 NLM ISO Abbreviation: Lab Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8<superscript>+</superscript> T cells in a mouse model of mammary carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Hinshaw+DC%22">Hinshaw DC</searchLink>; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Swain+CA%22">Swain CA</searchLink>; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Chen+D%22">Chen D</searchLink>; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.; Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.; Center for Clinical and Translational Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Hanna+A%22">Hanna A</searchLink>; Vanderbilt Center for Immunobiology, Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Molina+PA%22">Molina PA</searchLink>; Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Maynard+CL%22">Maynard CL</searchLink>; Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Lee+G%22">Lee G</searchLink>; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22McFarland+BC%22">McFarland BC</searchLink>; Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Samant+RS%22">Samant RS</searchLink>; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.; Birmingham VA Medical Center, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Shevde+LA%22">Shevde LA</searchLink>; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA. lsamant@uab.edu.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA. lsamant@uab.edu.
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  Data: <searchLink fieldCode="JN" term="%220376617%22">Laboratory investigation; a journal of technical methods and pathology</searchLink> [Lab Invest] 2022 Nov; Vol. 102 (11), pp. 1236-1244. <i>Date of Electronic Publication: </i>2022 Jul 30.
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  Data: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%22">Elsevier Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0376617 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1530-0307 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200236837%22">00236837 </searchLink><i>NLM ISO Abbreviation: </i>Lab Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41374-022-00828-1
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        Text: English
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              M: 11
              Text: 2022 Nov
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