QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.

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Title: QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.
Authors: Anwaier G; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Xie TT; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Pan CS; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Li AQ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Yan L; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Wang D; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Chen FK; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Weng DZ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Sun K; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Chang X; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Fan JY; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Han JY; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Liu J; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China.; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China.; Key Laboratory of Microcirculation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China.; State Key Laboratory of Core Technology in Innovative Chinese Medicine, Tianjin, China.; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2022 Jul 13; Vol. 13, pp. 918335. Date of Electronic Publication: 2022 Jul 13 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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