Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice.

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Title: Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice.
Authors: Wang S; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Ichinomiya T; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA.; Department of Anesthesiology, Nagasaki University Hospital, Nagasaki, Japan., Savchenko P; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Wang D; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Sawada A; Department of Anesthesiology, Sapporo Medical University School of Medicine, Sapporo, Japan., Li X; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Duong T; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Li W; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Bonds JA; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Kim EJ; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA.; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, South Korea., Miyanohara A; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Roth DM; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Patel HH; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Patel PM; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Tadokoro T; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA.; Department of Anesthesiology, University of the Ryukyus, Okinawa, Japan., Marsala M; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA.; Neuroregeneration Laboratory, Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA., Head BP; Department of Anesthesiology, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Anesthesiology, University of California San Diego, La Jolla, CA, USA.
Source: Theranostics [Theranostics] 2022 Jul 11; Vol. 12 (12), pp. 5389-5403. Date of Electronic Publication: 2022 Jul 11 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1838-7640
DOI:10.7150/thno.72614