Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.

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Title: Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.
Authors: Gupta S; Department of Genetics, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Dovey OM; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK., Domingues AF; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Cyran OW; Department of Haematology, University of Cambridge, Cambridge, UK., Cash CM; College of Health, Medicine and Life Sciences - Division of Biosciences, Brunel University London, Uxbridge, UK., Giotopoulos G; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Rak J; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Cooper J; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.; Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Gozdecka M; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Dijkhuis L; College of Health, Medicine and Life Sciences - Division of Biosciences, Brunel University London, Uxbridge, UK., Asby RJ; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Al-Jabery N; College of Health, Medicine and Life Sciences - Division of Biosciences, Brunel University London, Uxbridge, UK., Hernandez-Hernandez V; College of Health, Medicine and Life Sciences - Division of Biosciences, Brunel University London, Uxbridge, UK.; Centre for Genome Engineering and Maintenance, Brunel University London, Uxbridge, UB8 3PH, UK., Prabakaran S; NonExomics Inc., Boston, MA, USA., Huntly BJ; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Vassiliou GS; Department of Haematology, University of Cambridge, Cambridge, UK.; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.; Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK., Pina C; College of Health, Medicine and Life Sciences - Division of Biosciences, Brunel University London, Uxbridge, UK.; Centre for Genome Engineering and Maintenance, Brunel University London, Uxbridge, UB8 3PH, UK.
Source: Science advances [Sci Adv] 2022 Aug 05; Vol. 8 (31), pp. eabn4886. Date of Electronic Publication: 2022 Aug 03.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2375-2548
DOI:10.1126/sciadv.abn4886