Accurate determination of CRISPR-mediated gene fitness in transplantable tumours.
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| Title: | Accurate determination of CRISPR-mediated gene fitness in transplantable tumours. |
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| Authors: | Eirew P; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., O'Flanagan C; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Ting J; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Salehi S; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Brimhall J; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada.; AbCellera Biologics Inc., Vancouver, BC, Canada., Wang B; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Biele J; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada.; AbCellera Biologics Inc., Vancouver, BC, Canada., Algara T; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Lee SR; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Hoang C; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada.; British Columbia Institute of Technology, Vancouver, BC, Canada., Yap D; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., McKinney S; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Bates C; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Kong E; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Lai D; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Beatty S; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Andronescu M; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Zaikova E; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada., Funnell T; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Ceglia N; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Chia S; Department of Medical Oncology, BC Cancer, Vancouver, BC, Canada., Gelmon K; Department of Medical Oncology, BC Cancer, Vancouver, BC, Canada., Mar C; Department of Diagnostic Radiology, BC Cancer, Vancouver, BC, Canada., Shah S; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Roth A; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; Department of Computer Science, University of British Columbia, Vancouver, BC, Canada., Bouchard-Côté A; Department of Statistics, University of British Columbia, Vancouver, BC, Canada. bouchard@stat.ubc.ca., Aparicio S; Department of Molecular Oncology, BC Cancer, Vancouver, BC, Canada. saparicio@bccrc.ca.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. saparicio@bccrc.ca. |
| Source: | Nature communications [Nat Commun] 2022 Aug 04; Vol. 13 (1), pp. 4534. Date of Electronic Publication: 2022 Aug 04. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-022-31830-2 |
